TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4)
DOI: http://doi.org/10.22427/NTP-OTHER-1
Study Results
Genetic Toxicology
| Micronucleus - Rats |
|---|
View
|
View
|
View
|
View
|
Citation Information
NTP. TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).
Publications
TOX-96
NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
Study Data
Toxicity and Carcinogenicity Studies
28-Day Evaluation of the Toxicity (C06100) of Perfluorohexane sulfonate potassium salt (PFHSKslt) (3871-99-6) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E01 - Animal Removal Summary By Treatment Group (12 kB)
- E02 - Animals Removed from Experiment (67 kB)
- E03 - Growth Curves (368 kB)
- E04 - Mean Body Weights and Survival Table (16 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (29 kB)
- P04 - Neoplasms by Individual Animal (215 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (217 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (75 kB)
- P11 - Statistical Analysis of Survival Data (28 kB)
- P14 - Individual Animal Pathology Data (276 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (216 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (30 kB)
- P40 - Survival Curves (427 kB)
- PA06 - Organ Weights Summary Females (71 kB)
- PA06 - Organ Weights Summary Males (71 kB)
- PA41 - Clinical Chemistry Summary Females (164 kB)
- PA41 - Clinical Chemistry Summary Males (164 kB)
- PA43 - Hematology Summary Females (149 kB)
- PA43 - Hematology Summary Males (148 kB)
- PA45 - Liver Special Studies Summary (36 kB)
- PA48 - Summary of Tissue Concentration Males (54 kB)
- PA48 - Summary of Tissue Concentration Females (42 kB)
- R06 - Andrology Summary (50 kB)
- R07 - Hormone Summary Females (43 kB)
- R07 - Hormone Summary Males (46 kB)
- Results of Vaginal Cytology Study Using Transition Matrix Approach (44 kB)
- Summary of Estrous Stages and Cycle Data (54 kB)
- Vaginal Cytology Plot (17 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Non Neoplastic Pathology Data (20 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Individual Animal Andrology Data (7 kB)
- Individual Animal Clinical Chemistry Data Females (10 kB)
- Individual Animal Clinical Chemistry Data Males (11 kB)
- Individual Animal Hematology Data Females (12 kB)
- Individual Animal Hematology Data Males (12 kB)
- Individual Animal Hormone Data Females (8 kB)
- Individual Animal Hormone Data Males (8 kB)
- Individual Animal Liver Special Studies Data (6 kB)
- Individual Animal Organ Weight Data Females (9 kB)
- Individual Animal Organ Weight Data Males (10 kB)
- Individual Animal Tissue Concentration Data Females (7 kB)
- Individual Animal Tissue Concentration Data Males (7 kB)
- Individual Vaginal Cytology Data (25 kB)
- Individual_Animal_PCR_Data (24 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (35 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Clinical Observations (2 kB)
28-Day Evaluation of the Toxicity (C07040) of Perfluorobutane sulfonate (PFBS) (375-73-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E01 - Animal Removal Summary By Treatment Group (13 kB)
- E02 - Animals Removed from Experiment (67 kB)
- E03 - Growth Curves (379 kB)
- E04 - Mean Body Weights and Survival Table (16 kB)
- E05 - Clinical Observations Summary (18 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (37 kB)
- P04 - Neoplasms by Individual Animal (258 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (279 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (204 kB)
- P11 - Statistical Analysis of Survival Data (28 kB)
- P14 - Individual Animal Pathology Data (295 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (259 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (36 kB)
- P40 - Survival Curves (421 kB)
- PA06 - Organ Weights Summary (112 kB)
- PA41 - Clinical Chemistry Summary (Revised) (259 kB)
- PA43 - Hematology Summary (263 kB)
- PA45 - Liver Special Studies Summary (31 kB)
- PA48 - Summary of Tissue Concentration (71 kB)
- R06 - Andrology Summary (50 kB)
- R07 - Hormone Summary (61 kB)
- Results of Vaginal Cytology Study Using Transition Matrix Approach (42 kB)
- Summary of Estrous Stages and Cycle Data (59 kB)
- Vaginal Cytology Plot (17 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Non Neoplastic Pathology Data (52 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Female Individual Clinical Observations (5 kB)
- Individual Animal Andrology Data (7 kB)
- Individual Animal Clinical Chemistry Data (15 kB)
- Individual Animal Hematology Data (17 kB)
- Individual Animal Hormone Data (11 kB)
- Individual Animal Liver Special Studies Data (6 kB)
- Individual Animal Organ Weight Data (13 kB)
- Individual Animal Tissue Concentration Data (10 kB)
- Individual Vaginal Cytology Data (24 kB)
- Individual_Animal_PCR_Data (23 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (69 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Clinical Observations (3 kB)
28-Day Evaluation of the Toxicity (C20617) of Perfluorooctane Sulfonate (PFOS) (1763-23-1) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E01 - Animal Removal Summary By Treatment Group (12 kB)
- E02 - Animals Removed from Experiment (66 kB)
- E03 - Growth Curves (363 kB)
- E04 - Mean Body Weights and Survival Table (16 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (215 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (227 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (141 kB)
- P11 - Statistical Analysis of Survival Data (27 kB)
- P14 - Individual Animal Pathology Data (279 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (217 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 kB)
- P40 - Survival Curves (399 kB)
- PA06 - Organ Weights Summary (118 kB)
- PA41 - Clinical Chemistry Summary (307 kB)
- PA43 - Hematology Summary (276 kB)
- PA45 - Liver Special Studies Summary (36 kB)
- PA48 - Summary of Tissue Concentration (73 kB)
- R06 - Andrology Summary (50 kB)
- R07 - Hormone Summary (68 kB)
- Results of Vaginal Cytology Study Using Transition Matrix Approach (44 kB)
- Summary of Estrous Stages and Cycle Data (54 kB)
- Vaginal Cytology Plot (17 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Non Neoplastic Pathology Data (43 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Individual Animal Andrology Data (7 kB)
- Individual Animal Clinical Chemistry Data (16 kB)
- Individual Animal Hematology Data (18 kB)
- Individual Animal Hormone Data (11 kB)
- Individual Animal Liver Special Studies Data (6 kB)
- Individual Animal Organ Weight Data (15 kB)
- Individual Animal Tissue Concentration Data (10 kB)
- Individual Vaginal Cytology Data (23 kB)
- Individual_Animal_PCR_Data (25 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (52 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Clinical Observations (4 kB)
28-Day Evaluation of the Toxicity (C91069) of Wyeth 14,643 (WY) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E01 - Animal Removal Summary By Treatment Group (12 kB)
- E02 - Animals Removed from Experiment (47 kB)
- E03 - Growth Curves (346 kB)
- E04 - Mean Body Weights and Survival Table (15 kB)
- E05 - Clinical Observations Summary (12 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (165 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (171 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (134 kB)
- P11 - Statistical Analysis of Survival Data (23 kB)
- P14 - Individual Animal Pathology Data (196 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (166 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (33 kB)
- P40 - Survival Curves (387 kB)
- PA06 - Organ Weights Summary (95 kB)
- PA41 - Clinical Chemistry Summary (206 kB)
- PA43 - Hematology Summary (185 kB)
- PA45 - Liver Special Studies Summary (30 kB)
- R06 - Andrology Summary (50 kB)
- R07 - Hormone Summary (50 kB)
- Results of Vaginal Cytology Study Using Transition Matrix Approach (43 kB)
- Summary of Estrous Stages and Cycle Data (54 kB)
- Vaginal Cytology Plot (17 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (13 kB)
- Female Individual Animal Non Neoplastic Pathology Data (25 kB)
- Female Individual Animal Survival Data (8 kB)
- Female Individual Animal Terminal Body Weight Data (13 kB)
- Individual Animal Andrology Data (7 kB)
- Individual Animal Clinical Chemistry Data (12 kB)
- Individual Animal Hematology Data (14 kB)
- Individual Animal Hormone Data (9 kB)
- Individual Animal Liver Special Studies Data (5 kB)
- Individual Animal Organ Weight Data (12 kB)
- Individual Vaginal Cytology Data (24 kB)
- Individual_Animal_PCR_Data (20 kB)
- Male Individual Animal Body Weight Data (13 kB)
- Male Individual Animal Non Neoplastic Pathology Data (33 kB)
- Male Individual Animal Survival Data (8 kB)
- Male Individual Animal Terminal Body Weight Data (13 kB)
- Male Individual Clinical Observations (2 kB)