Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4)

DOI: http://doi.org/10.22427/NTP-OTHER-1


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4).
Micronucleus - Rats
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Positive

Citation Information


NTP. TOX-96: 1-Perfluorobutanesulfonic acid (375-73-5), Potassium perfluorohexanesulfonate (3871-99-6), Perfluorooctane sulfonate (1763-23-1), WY-14643 (50892-23-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-96 NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats

Study Data


Toxicity and Carcinogenicity Studies


28-Day Evaluation of the Toxicity (C06100) of Perfluorohexane sulfonate potassium salt (PFHSKslt) (3871-99-6) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C07040) of Perfluorobutane sulfonate (PFBS) (375-73-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C20617) of Perfluorooctane Sulfonate (PFOS) (1763-23-1) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
28-Day Evaluation of the Toxicity (C91069) of Wyeth 14,643 (WY) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Perfluorobutane Sulfonate (PFBS) (375-73-5) in Micronucleus Study G04006 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorohexane Sulfonate Potassium Salt (PFHSKslt) (3871-99-6) in Micronucleus Study G06100 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorooctane Sulfonate (1763-23-1) in Micronucleus Study G04004 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study G91069 in Harlan Sprague-Dawley Rats