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Nalidixic acid (389-08-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3020912

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
View
  • Clear Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Nalidixic acid (389-08-2).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Nalidixic acid (389-08-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Nalidixic acid (389-08-2).
Bacterial Mutagenicity
View
  • Negative
View
  • Weakly Positive

Citation Information

NTP. Nalidixic acid (389-08-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-368 Toxicology and Carcinogenesis Studies of Nalidixic Acid (CASRN 389-08-2) in F344/N Rats and B6C3F1 Mice (Feed Studies)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Nalidixic Acid (389-08-2) in Male F344 Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nalidixic Acid (389-08-2) in Female F344 Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nalidixic Acid (389-08-2) in Male B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nalidixic Acid (389-08-2) in Female B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Nalidixic Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 253916
Summary Data
Genetic Toxicity Evaluation of Nalidixic Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A06185
Summary Data

Other NTP Studies

ADME/TK Evaluation (S0209) of Nalidixic acid (389-08-2) in F344 Rats Exposed via Gavage Administration
Data Summary

NTP Data Collections