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TR-368: Nalidixic acid (389-08-2)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
View
  • Clear Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Equivocal Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-368: Nalidixic acid (389-08-2).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-368: Nalidixic acid (389-08-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-368: Nalidixic acid (389-08-2).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Negative

Citation Information

NTP. TR-368: Nalidixic acid (389-08-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-368 Toxicology and Carcinogenesis Studies of Nalidixic Acid (CASRN 389-08-2) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Nalidixic Acid (389-08-2) in Male F344 Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nalidixic Acid (389-08-2) in Female F344 Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nalidixic Acid (389-08-2) in Male B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nalidixic Acid (389-08-2) in Female B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Nalidixic Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 253916
Summary Data
Genetic Toxicity Evaluation of Nalidixic Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A06185
Summary Data