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2',3'-Dideoxyadenosine (4097-22-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2023771

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2',3'-Dideoxyadenosine (4097-22-7).
Micronucleus - Mice
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  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2',3'-Dideoxyadenosine (4097-22-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2',3'-Dideoxyadenosine (4097-22-7).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Positive

Citation Information

NTP. 2',3'-Dideoxyadenosine (4097-22-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

IMM90014 NTP Summary Reports on Immunotoxicology Vol. 1, No. 1-15: Immunotoxicity of Dideoxyadenosine In Female C57Bl/6 Mice
Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2',3'-Dideoxyadenosine (4097-22-7) in Micronucleus Study 918660 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2',3'-Dideoxyadenosine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 074637
Summary Data
Genetic Toxicity Evaluation of 2',3'-Dideoxyadenosine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A45663
Summary Data

Other NTP Studies

15-Day Immunotoxicity Evaluation (IMM90014) of 2',3'-Dideoxyadenosine (4097-22-7) in C57BL/6 Mice via Gavage
C57BL/6 Mice Individual and Summary Data
22/31-Day Immunotoxicity Evaluation (IMM90014) of 2',3'-Dideoxyadenosine (4097-22-7) in C57BL/6 Mice via Gavage
C57BL/6 Mice Individual and Summary Data

NTP Data Collections