U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

2',3'-Dideoxyadenosine (4097-22-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2023771


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2',3'-Dideoxyadenosine (4097-22-7).
Micronucleus - Mice
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2',3'-Dideoxyadenosine (4097-22-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2',3'-Dideoxyadenosine (4097-22-7).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Positive

Citation Information


NTP. 2',3'-Dideoxyadenosine (4097-22-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


IMM90014 NTP Summary Reports on Immunotoxicology Vol. 1, No. 1-15: Immunotoxicity of Dideoxyadenosine In Female C57Bl/6 Mice
Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2',3'-Dideoxyadenosine (4097-22-7) in Micronucleus Study 918660 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2',3'-Dideoxyadenosine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 074637
Summary Data
Genetic Toxicity Evaluation of 2',3'-Dideoxyadenosine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A45663
Summary Data

Other NTP Studies


15-Day Immunotoxicity Evaluation (IMM90014) of 2',3'-Dideoxyadenosine (4097-22-7) in C57BL/6 Mice via Gavage
22/31-Day Immunotoxicity Evaluation (IMM90014) of 2',3'-Dideoxyadenosine (4097-22-7) in C57BL/6 Mice via Gavage