Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Crotonaldehyde (4170-30-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8024864

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Crotonaldehyde (4170-30-3).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Crotonaldehyde (4170-30-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Crotonaldehyde (4170-30-3).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Crotonaldehyde (4170-30-3).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Crotonaldehyde (4170-30-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C56279B) of Crotonaldehyde (4170-30-3) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C56279B) of Crotonaldehyde (4170-30-3) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Crotonaldehyde (4170-30-3) in Micronucleus Study A99101 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Crotonaldehyde in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 097471
Summary Data

Other NTP Studies

ADME/TK Evaluation (S0069) of Crotonaldehyde (4170-30-3) in F344 Rats Exposed via Gavage Administration or Intravenous Injection
Study Report
Data Summary

DTT Data Collections