WY-14643 (50892-23-4)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4020290
Publications
TOX-62
Toxicity Studies of WY-14,643 (CAS No. 50892-23-4) Administered in Feed to Male Sprague-Dawley Rats, B6C3F1 Mice, and Syrian Hamsters
TOX-96
NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
TOX-97
NTP Report on the Toxicity Studies of Perfluorinated Compounds: Carboxylates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
Study Data
Toxicity and Carcinogenicity Studies
28-Day Evaluation of the Toxicity (C91069) of Wyeth 14,643 (WY) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E01 - Animal Removal Summary By Treatment Group (12 kB)
- E02 - Animals Removed from Experiment (47 kB)
- E03 - Growth Curves (346 kB)
- E04 - Mean Body Weights and Survival Table (15 kB)
- E05 - Clinical Observations Summary (12 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (165 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (171 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (134 kB)
- P11 - Statistical Analysis of Survival Data (23 kB)
- P14 - Individual Animal Pathology Data (196 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (166 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (33 kB)
- P40 - Survival Curves (387 kB)
- PA06 - Organ Weights Summary (95 kB)
- PA41 - Clinical Chemistry Summary (206 kB)
- PA43 - Hematology Summary (185 kB)
- PA45 - Liver Special Studies Summary (30 kB)
- R06 - Andrology Summary (50 kB)
- R07 - Hormone Summary (50 kB)
- Results of Vaginal Cytology Study Using Transition Matrix Approach (43 kB)
- Summary of Estrous Stages and Cycle Data (54 kB)
- Vaginal Cytology Plot (17 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (13 kB)
- Female Individual Animal Non Neoplastic Pathology Data (25 kB)
- Female Individual Animal Survival Data (8 kB)
- Female Individual Animal Terminal Body Weight Data (13 kB)
- Individual Animal Andrology Data (7 kB)
- Individual Animal Clinical Chemistry Data (12 kB)
- Individual Animal Hematology Data (14 kB)
- Individual Animal Hormone Data (9 kB)
- Individual Animal Liver Special Studies Data (5 kB)
- Individual Animal Organ Weight Data (12 kB)
- Individual Vaginal Cytology Data (24 kB)
- Individual_Animal_PCR_Data (20 kB)
- Male Individual Animal Body Weight Data (13 kB)
- Male Individual Animal Non Neoplastic Pathology Data (33 kB)
- Male Individual Animal Survival Data (8 kB)
- Male Individual Animal Terminal Body Weight Data (13 kB)
- Male Individual Clinical Observations (2 kB)
3-Month Evaluation of the Toxicity (C55550E) of Methapyrilene hydrochloride (135-23-9) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
2-Week Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
2-Week Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027D) of Peroxisome Project (WY-14643) (50892-23-4) in Syrian Golden Hamsters Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
Individual Animal Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study A06279 in Tg.AC (FVB/N) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study A71798 in Tg.AC (FVB/N) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Peroxisome Project (WY-14643) (50892-23-4) in Micronucleus Study G91069 in Harlan Sprague-Dawley Rats
Summary and Individual Animal Data
Other NTP Studies
Toxicokinetic Evaluation (S0583) of Wyeth-14643 (DTXSID4020290) in Rat, Mouse and Hamster
Toxicokinetic Evaluation (S0629) of Wyeth-14643 (DTXSID4020290) in Rat, Mouse and Hamster
Data
- Annotated Group Parameters (20 kB)
- Annotated Individual Animal Data (207 kB)
- Original Data (67 kB)
- Summary Data - Hamsters (206 kB)
- Summary Data - Mice (198 kB)
- Summary Data - Rats (200 kB)