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Dimethylvinyl chloride (513-37-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5020520


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Male, Rats
View
  • Clear Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Male, Mice
View
  • Clear Evidence, Male, Mice
View
  • Clear Evidence, Female, Mice
View
  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Dimethylvinyl chloride (513-37-1).
Micronucleus - Mice
View
  • Male: Positive
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Dimethylvinyl chloride (513-37-1).
Micronucleus - Rats
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Dimethylvinyl chloride (513-37-1).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Dimethylvinyl chloride (513-37-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Dimethylvinyl chloride (513-37-1).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dimethylvinyl chloride (513-37-1).
Bacterial Mutagenicity
View
  • Positive
View
  • Negative

Citation Information


NTP. Dimethylvinyl chloride (513-37-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-316 Toxicology and Carcinogenesis Studies of Dimethylvinyl Chloride (1-Chloro-2-Methylpropene) (CASRN 513-37-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Zeiger, E. Mutagenicity of 42 chemicals in Salmonella Environ. Molec. Mutagen. Vol. 16(Suppl 18) (1990) 32-54
Myhr B.C., McGregor, D., Bowers, L., Riach, C., Brown, A., Edwards, I., McBride, D., Martin, R., and Caspary, W.J. L5178Y mouse lymphoma cell mutation assay results with 41 compounds. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 138-167
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
Anderson, B.E., Zeiger, E., Shelby, M.D., Resnick, M.A., Gulati, D.K., Ivett, J.L., and Loveday, K.S. Chromosome aberration and sister chromatid exchange test results with 42 chemicals. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 55-137

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethylvinyl Chloride (DMVC) (513-37-1) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethylvinyl Chloride (DMVC) (513-37-1) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethylvinyl Chloride (DMVC) (513-37-1) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethylvinyl Chloride (DMVC) (513-37-1) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethylvinyl Chloride (DMVC) (513-37-1) in Female B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethylvinyl Chloride (DMVC) (513-37-1) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Dimethylvinyl Chloride (DMVC) (513-37-1) in Micronucleus Study A35968 in F344 Rats
Genetic Toxicity Evaluation of Dimethylvinyl Chloride (DMVC) (513-37-1) in Micronucleus Study A50288 in B6C3F1 Mice
Genetic Toxicity Evaluation of Dimethylvinyl Chloride (DMVC) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 327442
Summary Data
Genetic Toxicity Evaluation of Dimethylvinyl Chloride (DMVC) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 397636
Summary Data