2,4-Dimethoxyaniline hydrochloride (54150-69-5)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1020483
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Bacterial Mutagenicity |
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Publications
TR-171
Bioassay of 2,4-Dimethoxyaniline Hydrochloride for Possible Carcinogenicity (CASRN 54150-69-5)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Dimethoxyaniline Hydrochloride (54150-69-5) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Dimethoxyaniline Hydrochloride (54150-69-5) in Female F344 Rats Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of 2,4-Dimethoxyaniline Hydrochloride (54150-69-5) in Micronucleus Study 756856 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2,4-Dimethoxyaniline Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 792648
Summary Data
- G06 - Ames Summary Data (64 KB)