Glycidol (556-52-5)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4020666
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity | |
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SLRL | RT |
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Bacterial Mutagenicity |
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Publications
Study Data
Toxicity and Carcinogenicity Studies
40-Week Evaluation of the Toxicity (C99035) of Transgenic Model II (Glycidol) (556-52-5) in P16(INK4A)/(+/-) (C57BL/6) Mice Exposed via Gavage. NTP Special Study
26-39 Week Evaluation of the Toxicity (C99035) of Transgenic Model II (Glycidol) (556-52-5) in Tg.P16-INK4A Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity of Glycidol (556-52-5) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Glycidol (556-52-5) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Glycidol (556-52-5) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Glycidol (556-52-5) in Female B6C3F1 Mice Exposed via Gavage
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Glycidol (556-52-5) in Micronucleus Study 196476 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Glycidol (556-52-5) in Micronucleus Study A37837 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Glycidol (556-52-5) in Micronucleus Study A48958 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Glycidol (556-52-5) in Micronucleus Study A58625 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Glycidol (556-52-5) in Micronucleus Study A75768 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Glycidol (556-52-5) in Micronucleus Study A92101 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Glycidol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 278371
Summary Data
- G06 - Ames Summary Data (146 KB)
Genetic Toxicity Evaluation of Glycidol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 971355
Summary Data
- G06 - Ames Summary Data (148 KB)
Other NTP Studies
14-Day Immunotoxicity Evaluation (IMM91019) of Glycidol (556-52-5) in B6C3F1 Mice via Gavage
B6CF1 Mice Individual and Summary Data
- Absolute Leukocyte Differentials (13 kB)
- Body Weights (87 kB)
- Hematology (13 kB)
- Host Resistance to B16F10 Melanoma Tumors (4 kB)
- In Vitro Cytotoxic T Lymphocyte (CTL) Assay (13 kB)
- Lymphocyte Proliferation (13 kB)
- Mixed Leukocyte Response (9 kB)
- Natural Killer Activity (10 kB)
- Organ Weights (20 kB)
- Resistance to Infection with Listeria Monocytogenes (28 kB)
- Resistance to Infection with Streptococcus Pneumoniae (28 kB)
- Reticulocytes (8 kB)
- Surface Markers (%) (12 kB)
- Surface Markers (Absol) (11 kB)
- T-Dependent AB Response Day 4 (12 kB)