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Sucrose (57-50-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2021288

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Sucrose (57-50-1).
Mammalian Cell Mutagenicity
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  • Negative
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  • Negative
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  • Negative

Citation Information

NTP. Sucrose (57-50-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Myhr, B.C., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 103-194
Mitchell, A.D., Rudd, C.J., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for 63 coded chemicals tested at SRI International. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 37-102
McGregor, D.B., Martin, R., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. I. Results for nine compounds. Environ. Mutagen. Vol. 9 (1987) 143-160
Comparative investigation of the potential of glyphosate and glyphosate-based formulations (GBFs) to cause oxidative stress and DNA damage in human skin and liver cell systems Stephanie L. Smith-Roe1, Michael J. DeVito1, Caroll Co2, Sreenivasa C. Ramaiahgari1, Michael Easterling2, Julie R. Rice1, Paul E. Dunlap1, David M. Crizer1, Zhifeng Zhou1, B. Alex Merrick1, Guanhua Xie2, Shawn F. Harris2, Keith R. Shockley3, Arpit Tandon4, Ayse Oktay4, Deepak Mav4, Ruchir Shah4, Alexandre Borrel4, Vijay Gombar4, Scott A. Masten1, Richard S. Paules1, Stephen S. Ferguson1*

Affiliations
1Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
2DLH, LLC, Bethesda, Maryland, USA.
3Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
4Sciome, Durham, North Carolina, USA.

*Corresponding Author
Stephen S. Ferguson, Ph.D.
Mechanistic Toxicology Branch
Division of Translational Toxicology
National Institute of Environmental Health Sciences
111 TW Alexander Dr.
Building 101, Room E140B
P.O. Box 12233
Research Triangle Park, NC 27709
Email: stephen.ferguson@nih.gov; (984)287-3128

DOI: https://doi.org/10.22427/NTP-DATA-500-106-001-000-3
The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals using High Throughput Transcriptomics and Benchmark Concentration Modeling Ramaiahgari SC, Auerbach SS, Saddler TO, Rice JR, Dunlap PE, Sipes NS, DeVito MJ, Shah RR, Bushel PR, Merrick BA, Paules RS, Ferguson SS

Toxicological Sciences (2019) DOI: https://doi.org/10.1093/toxsci/kfz065 PMID: 30850835
CEBS DOI: https://doi.org/10.22427/NTP-DATA-002-00058-0001-0000-6
SRA No. SRP166108; BioProject No. PRJNA497448

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