Hydrochlorothiazide (58-93-5)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2020713
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity |
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Bacterial Mutagenicity |
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Publications
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of Hydrochlorothiazide (58-93-5) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Hydrochlorothiazide (58-93-5) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Hydrochlorothiazide (58-93-5) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Hydrochlorothiazide (58-93-5) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Hydrochlorothiazide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 715548
Summary Data
- G06 - Ames Summary Data (143 KB)
Other NTP Studies
Prenatal Developmental Toxicity Study (TER84084) of Hydrochlorothiazide (58-93-5) in Sprague-Dawley Rats Exposed via Gavage
Individual and Summary Data
- Dam Data: Dam Body Weights (24 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Organ Weights (29 kB)
- Fetal Data: All Malformations (744 kB)
- Fetal Data: All Variations (744 kB)
- Fetal Data: Fetal Body Weights (739 kB)
- Live Litter: All Litter (741 kB)
- Live Litter: Live Litter (745 kB)
Prenatal Developmental Toxicity Study (TER84085) of Hydrochlorothiazide (58-93-5) in Swiss CD-1 Mice Exposed via Gavage
Individual and Summary Data
- Dam Data: Dam Body Weights (16 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Organ Weights (19 kB)
- Fetal Data: All Malformations (407 kB)
- Fetal Data: All Variations (407 kB)
- Fetal Data: Fetal Body Weights (403 kB)
- Live Litter: All Litter (405 kB)
- Live Litter: Live Litter (408 kB)