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Oxazepam (604-75-1)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Oxazepam (604-75-1).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Oxazepam (604-75-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Oxazepam (604-75-1).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Oxazepam (604-75-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-443 Toxicology and Carcinogenesis Studies of Oxazepam (CASRN 604-75-1) in Swiss-Webster and B6C3F1 Mice (Feed Studies)
TR-468 Toxicology and Carcinogenesis Studies of Oxazepam (CASRN 604-75-1) in F344/N Rats (Feed Studies)
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C62453) of Oxazepam (604-75-1) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C62453) of Oxazepam (604-75-1) in Swiss-Webster Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C62453B) of Oxazepam (604-75-1) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C62453) of Oxazepam (604-75-1) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C62453) of Oxazepam (604-75-1) in Swiss-Webster Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Oxazepam (604-75-1) in Micronucleus Study A98656 in B6C3F1 Mice
Genetic Toxicity Evaluation of Oxazepam in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 307396
Summary Data

Other NTP Studies


Toxicokinetic Evaluation (S0301) of Oxazepam (604-75-1) in F344/N Rats and B6C3F1 or Swiss Webster Mice Exposed via Dosed Feed, Intravenous Injection or Gavage
Data
Toxicokinetic Evaluation (S0578) of Oxazepam (604-75-1) in F344/N Rats Exposed via Dosed Feed
Data