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Oxazepam (604-75-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1021087


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Oxazepam (604-75-1).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Oxazepam (604-75-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Oxazepam (604-75-1).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Oxazepam (604-75-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-443 Toxicology and Carcinogenesis Studies of Oxazepam (CASRN 604-75-1) in Swiss-Webster and B6C3F1 Mice (Feed Studies)
TR-468 Toxicology and Carcinogenesis Studies of Oxazepam (CASRN 604-75-1) in F344/N Rats (Feed Studies)
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C62453) of Oxazepam (604-75-1) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C62453) of Oxazepam (604-75-1) in Swiss-Webster Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C62453B) of Oxazepam (604-75-1) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C62453) of Oxazepam (604-75-1) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C62453) of Oxazepam (604-75-1) in Swiss-Webster Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Oxazepam (604-75-1) in Micronucleus Study A98656 in B6C3F1 Mice
Genetic Toxicity Evaluation of Oxazepam in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 307396
Summary Data

Other NTP Studies


Toxicokinetic Evaluation (S0301) of oxazepam (DTXSID1021087) in Rat and Mouse
Toxicokinetic Evaluation (S0578) of oxazepam (DTXSID1021087) in Rat