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tert-Butyl hydroperoxide (75-91-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9024693


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to tert-Butyl hydroperoxide (75-91-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to tert-Butyl hydroperoxide (75-91-2).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to tert-Butyl hydroperoxide (75-91-2).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. tert-Butyl hydroperoxide (75-91-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
Comparative investigation of the potential of glyphosate and glyphosate-based formulations (GBFs) to cause oxidative stress and DNA damage in human skin and liver cell systems Stephanie L. Smith-Roe1, Michael J. DeVito1, Caroll Co2, Sreenivasa C. Ramaiahgari1, Michael Easterling2, Julie R. Rice1, Paul E. Dunlap1, David M. Crizer1, Zhifeng Zhou1, B. Alex Merrick1, Guanhua Xie2, Shawn F. Harris2, Keith R. Shockley3, Arpit Tandon4, Ayse Oktay4, Deepak Mav4, Ruchir Shah4, Alexandre Borrel4, Vijay Gombar4, Scott A. Masten1, Richard S. Paules1, Stephen S. Ferguson1*

Affiliations
1Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
2DLH, LLC, Bethesda, Maryland, USA.
3Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
4Sciome, Durham, North Carolina, USA.

*Corresponding Author
Stephen S. Ferguson, Ph.D.
Mechanistic Toxicology Branch
Division of Translational Toxicology
National Institute of Environmental Health Sciences
111 TW Alexander Dr.
Building 101, Room E140B
P.O. Box 12233
Research Triangle Park, NC 27709
Email: stephen.ferguson@nih.gov; (984)287-3128

DOI: https://doi.org/10.22427/NTP-DATA-500-106-001-000-3

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C20215) of tert-Butyl Hydroperoxide (75-91-2) in F344/N Rats Exposed via Topical Application
2-Week Evaluation of the Toxicity (C20215B) of tert-Butyl Hydroperoxide (75-91-2) in F344/N Rats Exposed via Gavage
2-Week Evaluation of the Toxicity (C20215) of tert-Butyl Hydroperoxide (75-91-2) in B6C3F1 Mice Exposed via Topical Application
2-Week Evaluation of the Toxicity (C20215B) of tert-Butyl Hydroperoxide (75-91-2) in B6C3F1 Mice Exposed via Gavage