Dimethyl methylphosphonate (756-79-6)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020494
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
Drosophila Germ Cell Mutagenicity | |
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SLRL | RT |
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Bacterial Mutagenicity |
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Publications
TR-323
Toxicology and Carcinogenesis Studies of Dimethyl Methylphosphonate (CASRN 756-79-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Dunnick JK, Eustis SL, Haseman JK. Development of kidney tumors in the male F344/N rat after treatment with dimethyl methylphosphonate. Fundam Appl Toxicol. 1988 Jul;11(1):91-9. doi: 10.1016/0272-0590(88)90273-4. PMID: 3209020
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethyl Methylphosphonate (756-79-6) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethyl Methylphosphonate (756-79-6) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethyl Methylphosphonate (756-79-6) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Dimethyl Methylphosphonate (756-79-6) in Female B6C3F1 Mice Exposed via Gavage
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Dimethyl Methylphosphonate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 842521
Summary Data
- G06 - Ames Summary Data (134 KB)