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Butyl benzyl phthalate (85-68-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3020205


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Inadequate Study, Male, Rats
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  • Positive, Female, Rats
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  • Equivocal Evidence, Female, Rats
  • Some Evidence, Male, Rats
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  • Equivocal Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Negative, Male, Mice
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  • Negative, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Butyl benzyl phthalate (85-68-7).
Rodent Cytogenetics
CA SCE
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Butyl benzyl phthalate (85-68-7).
Micronucleus - Mice
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  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Butyl benzyl phthalate (85-68-7).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Butyl benzyl phthalate (85-68-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Butyl benzyl phthalate (85-68-7).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Butyl benzyl phthalate (85-68-7).
Bacterial Mutagenicity
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  • Negative
View
  • Negative

Citation Information


NTP. Butyl benzyl phthalate (85-68-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-213 Carcinogenesis Bioassay of Butyl Benzyl Phthalate (CASRN 85-68-7) in F344/N Rats and B6C3F1 Mice (Feed Study)
TR-458 Toxicology and Carcinogenesis Studies of Butyl Benzyl Phthalate (CASRN 85-68-7) in F344 Rats (Feed Studies)
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
Final Report on the Developmental Toxicity Evaluation of Butyl Benzyl Phthalate Administered in Feed to Swiss Albino (CD-1) Mice on Gestational Days 6 to 15
Final Report on the Developmental Toxicity Evaluation of Butyl Benzyl Phthalate Administered in Feed to Swiss Albino (CD-1) Mice on Gestational Days 6 to 15--Laboratory Supplement
Developmental Toxicity Evaluation of Butyl Benzyl Pthalate Administered in Feed to CD Rats on Gestational Days 6 to 15
Myhr, B. and Caspary, W. Chemical mutagenesis at the TK locus in L5178Y mouse lymphoma cells. I. Results for 31 coded compounds in the National Toxicology Program. Environ. Molec. Mutagen. Vol. 18 (1991) 51-83
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Toxicity and Carcinogenicity Studies


26-Week Evaluation of the Toxicity (C54375B) of Butyl Benzyl Phthalate (85-68-7) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butyl Benzyl Phthalate (85-68-7) in Male F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Butyl Benzyl Phthalate (85-68-7) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butyl Benzyl Phthalate (85-68-7) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butyl Benzyl Phthalate (85-68-7) in Female B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C54375C) of Butyl Benzyl Phthalate (85-68-7) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C54375C) of Butyl Benzyl Phthalate (85-68-7) in F344/N Rats Exposed via Dosed Feed

Other NTP Studies


ADME/TK Evaluation (S0049) of Butyl benzyl phthalate (85-68-7) in F344 Rats Exposed via Dermal Application
Prenatal Developmental Toxicity Study (TER88025) of Butyl Benzyl Phthalate (85-68-7) in Sprague-Dawley Rats Exposed via Dosed Feed
Prenatal Developmental Toxicity Study (TER89026) of Butyl Benzyl Phthalate (85-68-7) in Swiss CD-1 Mice Exposed via Dosed Feed