Butyl benzyl phthalate (85-68-7)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3020205
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Rodent Cytogenetics | |
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CA | SCE |
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Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity |
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SLRL |
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Bacterial Mutagenicity |
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Publications
TR-213
Carcinogenesis Bioassay of Butyl Benzyl Phthalate (CASRN 85-68-7) in F344/N Rats and B6C3F1 Mice (Feed Study)
TR-458
Toxicology and Carcinogenesis Studies of Butyl Benzyl Phthalate (CASRN 85-68-7) in F344 Rats (Feed Studies)
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
Final Report on the Developmental Toxicity Evaluation of Butyl Benzyl Phthalate Administered in Feed to Swiss Albino (CD-1) Mice on Gestational Days 6 to 15
Final Report on the Developmental Toxicity Evaluation of Butyl Benzyl Phthalate Administered in Feed to Swiss Albino (CD-1) Mice on Gestational Days 6 to 15--Laboratory Supplement
Developmental Toxicity Evaluation of Butyl Benzyl Pthalate Administered in Feed to CD Rats on Gestational Days 6 to 15
Myhr, B. and Caspary, W. Chemical mutagenesis at the TK locus in L5178Y mouse lymphoma cells. I. Results for 31 coded compounds in the National Toxicology Program. Environ. Molec. Mutagen. Vol. 18 (1991) 51-83
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
Study Data
Toxicity and Carcinogenicity Studies
26-Week Evaluation of the Toxicity (C54375B) of Butyl Benzyl Phthalate (85-68-7) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butyl Benzyl Phthalate (85-68-7) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butyl Benzyl Phthalate (85-68-7) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butyl Benzyl Phthalate (85-68-7) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butyl Benzyl Phthalate (85-68-7) in Female B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C54375C) of Butyl Benzyl Phthalate (85-68-7) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C54375C) of Butyl Benzyl Phthalate (85-68-7) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Butyl Benzyl Phthalate (85-68-7) in Micronucleus Study A61034 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Butyl Benzyl Phthalate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 834175
Summary Data
- G06 - Ames Summary Data (128 KB)
Genetic Toxicity Evaluation of Butyl Benzyl Phthalate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 933175
Summary Data
- G06 - Ames Summary Data (134 KB)
Other NTP Studies
ADME/TK Evaluation (S0049) of Butyl benzyl phthalate (85-68-7) in F344 Rats Exposed via Dermal Application
Prenatal Developmental Toxicity Study (TER88025) of Butyl Benzyl Phthalate (85-68-7) in Sprague-Dawley Rats Exposed via Dosed Feed
Individual and Summary Data
- Dam Data: Dam Body Weights (27 kB)
- Dam Data: Dam Feed Consumption (24 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Dam Water Consumption (25 kB)
- Dam Data: Organ Weights (24 kB)
- Fetal Data: All Malformations (860 kB)
- Fetal Data: All Variations (860 kB)
- Fetal Data: Fetal Body Weights (855 kB)
- Live Litter: All Litter (857 kB)
- Live Litter: Live Litter (861 kB)
Prenatal Developmental Toxicity Study (TER89026) of Butyl Benzyl Phthalate (85-68-7) in Swiss CD-1 Mice Exposed via Dosed Feed
Individual and Summary Data
- Dam Data: Dam Body Weights (26 kB)
- Dam Data: Dam Feed Consumption (22 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Dam Water Consumption (22 kB)
- Dam Data: Organ Weights (28 kB)
- Fetal Data: All Malformations (701 kB)
- Fetal Data: All Variations (701 kB)
- Fetal Data: Fetal Body Weights (696 kB)
- Live Litter: All Litter (698 kB)
- Live Litter: Live Litter (701 kB)