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Pentachlorophenol (87-86-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7021106

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice
View
  • Clear Evidence, Male, Mice
  • Some Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Pentachlorophenol (87-86-5).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Pentachlorophenol (87-86-5).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Pentachlorophenol (87-86-5).
Mammalian Cell Cytogenetics
CA SCE
  • View
    • Weakly Positive
  • View
    • Weakly Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Pentachlorophenol (87-86-5).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. Pentachlorophenol (87-86-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-349 Toxicology and Carcinogenesis Studies of Two Pentachlorophenol Technical-Grade Mixtures (CASRN 87-86-5) in B6C3F1 Mice (Feed Studies)
TR-483 Toxicology and Carcinogenesis Studies of Pentachlorophenol (CASRN 87-86-5) in F344/N Rats (Feed Studies)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
Systematic Evaluation of the Application of Zebrafish in Toxicology (SEAZIT): Interlaboratory Study Dose Range Finding (DRF) data DOI: https://doi.org/10.22427/NTP-DATA-002-00102-0001-000-6

Study Data

Protocol

Toxicity and Carcinogenicity Studies

18-33 Day Evaluation of the Toxicity (C89002) of Pentachlorophenol, Purified (87-86-5) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
26-Week Evaluation of the Toxicity (C89002B) of Transgenic LECM (Pentachlorophenol) (87-86-5) in P53(C57BL/6) Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
26-Week Evaluation of the Toxicity (C89002C) of Transgenic LECM (Pentachlorophenol) (87-86-5) in Tg.AC Mice Exposed via Topical Application
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C89002) of Pentachlorophenol, Purified (87-86-5) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55378) of Pentachlorophenol, Technical (87-86-5) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55389) of Pentachlorophenol, Dowicide EC-7 (87-86-5) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Pentachlorophenol, Dowicide EC-7 (87-86-5) in Micronucleus Study A54434 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Pentachlorophenol, Dowicide EC-7 (87-86-5) in Micronucleus Study A84354 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Pentachlorophenol, Technical in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 771899
Summary Data

Other NTP Studies

Toxicokinetic Evaluation (S0328) of Pentachlorophenol (DTXSID7021106) in Rat
Data
Toxicokinetic Evaluation (S0579) of Pentachlorophenol (DTXSID7021106) in Rat
Data

NTP Data Collections