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Cumene (98-82-8)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Male, Rats
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Cumene (98-82-8).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Cumene (98-82-8).
Micronucleus - Rats
View
  • Male: Negative
View
  • Male: Positive
An overview of Genetic Toxicology In Vivo Alkaline Comet Assay Mice study conclusions related to Cumene (98-82-8).
In Vivo Alkaline Comet Assay - Mice
View
  • Male: Negative
    Female: Positive
An overview of Genetic Toxicology In Vivo Alkaline Comet Assay Rats study conclusions related to Cumene (98-82-8).
In Vivo Alkaline Comet Assay - Rats
View
  • Male: Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Cumene (98-82-8).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. Cumene (98-82-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-542 Toxicology and Carcinogenesis Studies of Cumene (CASRN 98-82-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Study Data


Toxicity and Carcinogenicity Studies


26-Day Evaluation of the Toxicity (C96011) of Cumene (98-82-8) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
26-Day Evaluation of the Toxicity (C96011) of Cumene (98-82-8) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
2-Week Evaluation of the Toxicity (C96011) of Cumene (98-82-8) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C96011) of Cumene (98-82-8) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
2-Week Evaluation of the Toxicity (C96011) of Cumene (98-82-8) in B6C3F1 Mice via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C96011) of Cumene (98-82-8) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
3-Month Evaluation of the Toxicity (C96011) of Cumene (98-82-8) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C96011) of Cumene (98-82-8) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C96011) of Cumene (98-82-8) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C96011) of Cumene (98-82-8) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Cumene (98-82-8) in DNA Damage Study G1104ZE in F344 Rats
Genetic Toxicity Evaluation of Cumene (98-82-8) in DNA Damage Study G1104ZF in B6C3F1 Mice
Genetic Toxicity Evaluation of Cumene (98-82-8) in Micronucleus Study A60520 in B6C3F1 Mice
Genetic Toxicity Evaluation of Cumene (98-82-8) in Micronucleus Study A98265 in F344 Rats
Genetic Toxicity Evaluation of Cumene (98-82-8) in Micronucleus Study G1104ZC in F344 Rats
Genetic Toxicity Evaluation of Cumene (98-82-8) in Micronucleus Study G1104ZD in B6C3F1 Mice
Genetic Toxicity Evaluation of Cumene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A42965
Summary Data
Genetic Toxicity Evaluation of Cumene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G1104ZB
Summary Data