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Goldenseal root (GOLDENSEALRT)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6031384


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Goldenseal root (GOLDENSEALRT).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Goldenseal root (GOLDENSEALRT).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Goldenseal root (GOLDENSEALRT). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-562 Toxicology and Carcinogenesis Studies of Goldenseal Root Powder (HYDRASTIS CANADENSIS) in F344/N Rats and B6C3F1 Mice (Feed studies)
Final Study Report Developmental Toxicity Evaluation for Goldenseal Root Powder (Hydrastis Canadensis) Administered in the Feed to Sprague-Dawley (CD®) Rats on Gestational Days 6 to 20
FINAL STUDY REPORT DEVELOPMENTAL TOXICITY EVALUTATION FOR GOLDENSEAL ROOT POWDER (HYDRASTIS CANADENSIS) ADMINISTERED IN THE FEED TO SPRAGUE-DAWLWY (CD(r)) RATS ON GESTATIONAL DAYS 6 TO 20
Final Study Report Developmental Toxicity Evaluation for Goldenseal (Hydrastis canadensis) root powder Administered in the Feed to Swiss (CD-1®) Mice on Gestational Days 6-17
Final Study Report?Developmental Toxicity Evaluation for Goldenseal (Hydrastis canadensis) root powder Administered in the Feed to Swiss (CD-1®) Mice on Gestational Days 6-17

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in F344 Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344 Rats Exposed via Dosed Feed. NTP Special Study
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed
2-Week Evaluation of the Toxicity (C99007) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C99007B) of Goldenseal Root Powder (GOLDENSEALRT) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Goldenseal Root Powder (GOLDENSEALRT) in Micronucleus Study A21831 in B6C3F1 Mice
Genetic Toxicity Evaluation of Goldenseal Root Powder in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A83314
Summary Data

Other NTP Studies


Prenatal Developmental Toxicity Pilot Study (TRP98007) of Goldenseal Root Powder (GOLDENSEALRT) in Sprague-Dawley Rats Exposed via Dosed Feed
Prenatal Developmental Toxicity Pilot Study (TRP99007) of Goldenseal Root Powder (GOLDENSEALRT) in Swiss CD-1 Mice Exposed via Dosed Feed
Prenatal Developmental Toxicity Study (TER98007) of Goldenseal Root Powder (GOLDENSEALRT) in Sprague-Dawley Rats Exposed via Dosed Feed
Prenatal Developmental Toxicity Study (TER99004) of Goldenseal Root Powder (GOLDENSEALRT) in Swiss CD-1 Mice Exposed via Dosed Feed