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TR-263: 1,2-Dichloropropane (78-87-5)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
View
  • Equivocal Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Some Evidence, Male, Mice
View
  • Some Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-263: 1,2-Dichloropropane (78-87-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-263: 1,2-Dichloropropane (78-87-5).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Weakly Positive

Citation Information


NTP. TR-263: 1,2-Dichloropropane (78-87-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-263 Toxicology and Carcinogenesis Studies of 1,2-Dichloropropane (Propylene Dichloride) (CASRN 78-87-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloropropane (Propylene Dichloride) (78-87-5) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloropropane (Propylene Dichloride) (78-87-5) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloropropane (Propylene Dichloride) (78-87-5) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloropropane (Propylene Dichloride) (78-87-5) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 1,2-Dichloropropane (Propylene Dichloride) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 566847
Summary Data
Genetic Toxicity Evaluation of 1,2-Dichloropropane (Propylene Dichloride) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 627177
Summary Data