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TR-434: 1,3-Butadiene (106-99-0)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to TR-434: 1,3-Butadiene (106-99-0).
Rodent Cytogenetics
CA
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-434: 1,3-Butadiene (106-99-0).
Micronucleus - Mice
View
  • Male: Positive (Nonstandard Protocol)
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-434: 1,3-Butadiene (106-99-0).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-434: 1,3-Butadiene (106-99-0).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-434: 1,3-Butadiene (106-99-0).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. TR-434: 1,3-Butadiene (106-99-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-434 Toxicology and Carcinogenesis Studies of 1,3-Butadiene (CASRN 106-99-0) in B6C3F1 Mice (Inhalation Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 1,3-Butadiene (106-99-0) in Male B6C3F1 Mice via Whole Body Respiratory Exposure
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,3-Butadiene (106-99-0) in Female B6C3F1 Mice via Whole Body Respiratory Exposure
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C50602C) of 1,3-Butadiene (106-99-0) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 1,3-Butadiene (106-99-0) in Micronucleus Study A74454 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 1,3-Butadiene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 256166
Summary Data