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TR-439: Methylphenidate hydrochloride (298-59-9)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Some Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-439: Methylphenidate hydrochloride (298-59-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-439: Methylphenidate hydrochloride (298-59-9).
Bacterial Mutagenicity
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  • Negative
View
  • Negative

Citation Information


NTP. TR-439: Methylphenidate hydrochloride (298-59-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-439 Toxicology and Carcinogenesis Studies of Methylphenidate Hydrochloride (CASRN 298-59-9) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C56280B) of Methylphenidate Hydrochloride (298-59-9) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C56280B) of Methylphenidate Hydrochloride (298-59-9) in B6C3F1 Mice Exposed via Dosed Feed