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TR-477: 1-Chloro-2-propanol (127-00-4)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-477: 1-Chloro-2-propanol (127-00-4).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-477: 1-Chloro-2-propanol (127-00-4).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-477: 1-Chloro-2-propanol (127-00-4).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-477: 1-Chloro-2-propanol (127-00-4).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive
View
  • Positive

Citation Information


NTP. TR-477: 1-Chloro-2-propanol (127-00-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-477 Toxicology and Carcinogenesis Studies of 1-Chloro-2-Propanol (Technical Grade) (CASRN 127-00-4) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)

Study Data


Toxicity and Carcinogenicity Studies


26-Week Evaluation of the Toxicity (C61983D) of 1-Chloro-2-propanol, Technical (127-00-4) in P53(C57BL/6) Mice Exposed via Dosed Water
26-Week Evaluation of the Toxicity (C61983E) of 1-Chloro-2-propanol, Technical (127-00-4) in Tg.AC Mice Exposed via Topical Application
3-Month Evaluation of the Toxicity (C61983A) of 1-Chloro-2-propanol, Technical (127-00-4) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C61983A) of 1-Chloro-2-propanol, Technical (127-00-4) in B6C3F1 Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C61983C) of 1-Chloro-2-propanol, Technical (127-00-4) in F344/N Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C61983C) of 1-Chloro-2-propanol, Technical (127-00-4) in B6C3F1 Mice Exposed via Dosed Water

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 1-Chloro-2-propanol, Technical (127-00-4) in Micronucleus Study A34020 in B6C3F1 Mice
Genetic Toxicity Evaluation of 1-Chloro-2-propanol, Technical (127-00-4) in Micronucleus Study A61208 in Mice
Genetic Toxicity Evaluation of 1-Chloro-2-propanol, Technical in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 111503
Summary Data
Genetic Toxicity Evaluation of 1-Chloro-2-propanol, Technical in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 154127
Summary Data
Genetic Toxicity Evaluation of 1-Chloro-2-propanol, Technical in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 648348
Summary Data