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TR-498: p-Nitrotoluene (99-99-0)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Male, Rats
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Male, Mice
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-498: p-Nitrotoluene (99-99-0).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TR-498: p-Nitrotoluene (99-99-0).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-498: p-Nitrotoluene (99-99-0).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-498: p-Nitrotoluene (99-99-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-498: p-Nitrotoluene (99-99-0).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. TR-498: p-Nitrotoluene (99-99-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-498 Toxicology and Carcinogenesis Studies of p-Nitrotoluene (CASRN 99-99-0) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C62537D) of p-Nitrotoluene (99-99-0) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C62537D) of p-Nitrotoluene (99-99-0) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of p-Nitrotoluene (99-99-0) in Micronucleus Study A06877 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of p-Nitrotoluene (99-99-0) in Micronucleus Study A22897 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of p-Nitrotoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 828809
Summary Data