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TR-504: o-Nitrotoluene (88-72-2)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TR-504: o-Nitrotoluene (88-72-2).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-504: o-Nitrotoluene (88-72-2).
Micronucleus - Mice
View
  • Male: Equivocal
    Female: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-504: o-Nitrotoluene (88-72-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-504: o-Nitrotoluene (88-72-2).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information

NTP. TR-504: o-Nitrotoluene (88-72-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-504 Toxicology and Carcinogenesis Studies of o-Nitrotoluene (CASRN 88-72-2) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C62340D) of o-Nitrotoluene (88-72-2) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C62340D) of o-Nitrotoluene (88-72-2) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of o-Nitrotoluene (88-72-2) in Micronucleus Study A25222 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of o-Nitrotoluene (88-72-2) in Micronucleus Study A29734 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of o-Nitrotoluene (88-72-2) in Micronucleus Study A80173 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of o-Nitrotoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 192331
Summary Data
Genetic Toxicity Evaluation of o-Nitrotoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 692737
Summary Data