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TR-579: N,N-Dimethyl-p-toluidine (99-97-8)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-579: N,N-Dimethyl-p-toluidine (99-97-8).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
An overview of Genetic Toxicology In Vivo Alkaline Comet Assay Rats study conclusions related to TR-579: N,N-Dimethyl-p-toluidine (99-97-8).
In Vivo Alkaline Comet Assay - Rats
View
  • Male: Positive
An overview of Genetic Toxicology In Vivo Alkaline Comet Assay Mice study conclusions related to TR-579: N,N-Dimethyl-p-toluidine (99-97-8).
In Vivo Alkaline Comet Assay - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-579: N,N-Dimethyl-p-toluidine (99-97-8).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. TR-579: N,N-Dimethyl-p-toluidine (99-97-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-579 Toxicology and Carinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C20107) of N,N-Dimethyl-p-toluidine (99-97-8) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20107) of N,N-Dimethyl-p-toluidine (99-97-8) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20107) of N,N-Dimethyl-p-toluidine (99-97-8) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20107) of N,N-Dimethyl-p-toluidine (99-97-8) in B6C3F1 Mice Exposed via Gavage
Special Evaluation of the Toxicity (C20107) of N,N-Dimethyl-p-toluidine (99-97-8) in F344/N Rats Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of N,N-Dimethyl-p-toluidine (99-97-8) in DNA Damage Study G00059 in Sprague-Dawley Rats
Genetic Toxicity Evaluation of N,N-Dimethyl-p-toluidine (99-97-8) in DNA Damage Study G1104ZA in B6C3F1 Mice
Genetic Toxicity Evaluation of N,N-Dimethyl-p-toluidine (99-97-8) in Micronucleus Study A29310 in B6C3F1 Mice
Genetic Toxicity Evaluation of N,N-Dimethyl-p-toluidine (99-97-8) in Micronucleus Study G1104Z in B6C3F1 Mice
Genetic Toxicity Evaluation of N,N-Dimethyl-p-toluidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A14805
Summary Data
Genetic Toxicity Evaluation of N,N-Dimethyl-p-toluidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41919
Summary Data