TR-587: Tetrabromobisphenol A (79-94-7)
Study Results
Chronic Bioassay Level of Evidence
Rats | |
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Mice | |
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Genetic Toxicology
Micronucleus - Mice |
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Bacterial Mutagenicity |
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Publications
TR-587
Toxicology Studies of Tetrabromobisphenol A (CASRN 79-94-7) in F344/NTac Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Tetrabromobisphenol A in Wistar Han [Crl:WI(Han)] Rats and B6C3F1/N Mice (Gavage Studies)
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C20320) of Tetrabromobisphenol A (79-94-7) in F344/NTac Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (768 kB)
- E04 - Mean Body Weights and Survival Table (57 kB)
- E05 - Clinical Observations Summary (56 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (113 kB)
- P04 - Neoplasms by Individual Animal (1 mB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (149 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (108 kB)
- P14 - Individual Animal Pathology Data (263 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (118 kB)
- P40 - Survival Curves (816 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (35 kB)
- Female Individual Animal Clinical Observations (4 kB)
- Female Individual Animal Non Neoplastic Pathology Data (43 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (35 kB)
- Male Individual Animal Clinical Observations (3 kB)
- Male Individual Animal Neoplastic Pathology Data (2 kB)
- Male Individual Animal Non Neoplastic Pathology Data (45 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
3-Month Evaluation of the Toxicity (C20320) of Tetrabromobisphenol A (79-94-7) in B6C3F1/N Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (749 kB)
- E04 - Mean Body Weights and Survival Table (184 kB)
- E05 - Clinical Observations Summary (24 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (69 kB)
- P04 - Neoplasms by Individual Animal (1 mB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (94 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (46 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (90 kB)
- P40 - Survival Curves (811 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (34 kB)
- Female Individual Animal Non Neoplastic Pathology Data (5 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (34 kB)
- Male Individual Animal Non Neoplastic Pathology Data (14 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20320) of Tetrabromobisphenol A (79-94-7) in Wistar Han Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (70 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (22 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (54 kB)
- P04 - Neoplasms by Individual Animal (624 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (49 kB)
- P08 - Statistical Analysis of Primary Tumors (208 kB)
- P08 – Statistical Analysis of Primary Tumors of the Extended Uterine Evaluation (114 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (751 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (349 kB)
- P10 – Statistical Analysis of Non-neoplastic Lesions of the Extended Uterine Evaluation (119 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (598 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (56 kB)
- P40 - Survival Curves (66 kB)
- TBBPA Uterine Pathology in the Rats (426 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (441 kB)
- Female Individual Animal Clinical Observations (132 kB)
- Female Individual Animal Neoplastic Pathology Data (110 kB)
- Female Individual Animal Non Neoplastic Pathology Data (501 kB)
- Female Individual Animal Organ Weight Data (63 kB)
- Female Individual Animal Survival Data (37 kB)
- Male Individual Animal Body Weight Data (406 kB)
- Male Individual Animal Clinical Observations (105 kB)
- Male Individual Animal Neoplastic Pathology Data (82 kB)
- Male Individual Animal Non Neoplastic Pathology Data (550 kB)
- Male Individual Animal Organ Weight Data (63 kB)
- Male Individual Animal Survival Data (37 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20320) of Tetrabromobisphenol A (79-94-7) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (67 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (54 kB)
- P04 - Neoplasms by Individual Animal (651 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48 kB)
- P08 - Statistical Analysis of Primary Tumors (193 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (762 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (324 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (587 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (56 kB)
- P40 - Survival Curves (67 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (448 kB)
- Female Individual Animal Clinical Observations (29 kB)
- Female Individual Animal Neoplastic Pathology Data (79 kB)
- Female Individual Animal Non Neoplastic Pathology Data (366 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (427 kB)
- Male Individual Animal Clinical Observations (71 kB)
- Male Individual Animal Neoplastic Pathology Data (144 kB)
- Male Individual Animal Non Neoplastic Pathology Data (468 kB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Tetrabromobisphenol A (79-94-7) in Micronucleus Study A13260 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Tetrabromobisphenol A in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 968573
Summary Data
- G06 - Ames Summary Data (138 KB)
Genetic Toxicity Evaluation of Tetrabromobisphenol A in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G20033
Summary Data
- G06 - Ames Summary Data (80 KB)