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Pyridine (110-86-1)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Some Evidence, Male, Rats
View
  • Equivocal Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Pyridine (110-86-1).
Rodent Cytogenetics
CA
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Pyridine (110-86-1).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Pyridine (110-86-1).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Pyridine (110-86-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Pyridine (110-86-1).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Pyridine (110-86-1).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Pyridine (110-86-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-470 Toxicology and Carcinogenesis Studies of Pyridine (CASRN 110-86-1) in F344/N Rats, Wistar Rats, and B6C3F1 Mice (Drinking Water Studies)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
McGregor, D.B., Brown, A., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. II. 18 coded chemicals. Environ. Molec. Mutagen. Vol. 11 (1988) 91-118
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila. VIII. Reexamination of equivocal results. Environ. Molec. Mutagen. Vol. 19 (1992) 227-234

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C55301B) of Pyridine (110-86-1) in F344 Rats Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C55301B) of Pyridine (110-86-1) in Wistar Rats Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C55301B) of Pyridine (110-86-1) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
26-Week Evaluation of the Toxicity (C55301C) of Transgenic LECM (Pyridine) (110-86-1) in P53(C57BL/6) Mice Exposed via Dosed Water
26-Week Evaluation of the Toxicity (C55301D) of Transgenic LECM (Pyridine) (110-86-1) in Tg.AC Mice Exposed via Topical Application
3-Month Evaluation of the Toxicity (C55301B) of Pyridine (110-86-1) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C55301B) of Pyridine (110-86-1) in Wistar Outbred Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C55301B) of Pyridine (110-86-1) in B6C3F1 Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C55301B) of Pyridine (110-86-1) in F344/N Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C55301B) of Pyridine (110-86-1) in Wistar Outbred Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C55301B) of Pyridine (110-86-1) in B6C3F1 Mice Exposed via Dosed Water

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Pyridine (110-86-1) in Micronucleus Study A16600 in B6C3F1 Mice
Genetic Toxicity Evaluation of Pyridine (110-86-1) in Micronucleus Study A85799 in Mice
Genetic Toxicity Evaluation of Pyridine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 364799
Summary Data

Other NTP Studies


Toxicokinetic Evaluation (C55301B) of Pyridine (110-86-1) in F344/N Rats and B6C3F1 Mice Exposed via Gavage or Intravenous Injection
Toxicokinetic Evaluation (S0373) of Pyridine (110-86-1) in Rats Exposed via Intravenous Injection
Data