Sodium metavanadate (13718-26-8)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3044336
Publications
TOX-106
Toxicity Studies of Sodium Metavanadate and Vanadyl Sulfate Administered via Dosed Water to Harlan Sprague-Dawley Rats and B6C3F1 Mice
14-Day Toxicity Studies of Tetravalent and Pentavalent Vanadium Compounds in Harlan Sprague Dawley Rats and B6C3F1/N Mice via Drinking Water Exposure
Roberts GK, Stout MD, Sayers B, Fallacara DM, Hejtmancik MR, Waidyanatha S, Hooth MJ.
Toxicology Reports (2016) DOI: https://doi.org/10.1016/j.toxrep.2016.05.001 PMID: 28042531
Toxicology Reports (2016) DOI: https://doi.org/10.1016/j.toxrep.2016.05.001 PMID: 28042531
Evaluation of Immunotoxicity of Sodium Metavanadate Following Drinking Water Exposure in Female B6C3F1/N Mice in a 28-day Study
Rachel Frawley, Victor J. Johnson, Gary R. Burleson, Keith R Shockley, Mark F. Cesta, Greg Travlos, Michelle Cora, Georgia Roberts, Dori Germolec
TOX-106 Vanadium Compounds (Sodium Metavanadate and Vanadyl Sulfate): Abstract for TOX-106
DOI: https://doi.org/10.22427/NTP-DATA-500-001-001-000-7
TOX-106 Vanadium Compounds (Sodium Metavanadate and Vanadyl Sulfate): Abstract for TOX-106
DOI: https://doi.org/10.22427/NTP-DATA-500-001-001-000-7
Internal dose of vanadium in rats following repeated exposure to vanadyl sulfate and sodium orthovanadate via drinking water
James M. Harrington, Laura G. Haines, Keith E. Levine, Chamindu Liyanapatirana, Amal S. Essader, Reshan A. Fernando, Veronica G. Robinson, Georgia K. Roberts, Matthew D. Stout, Michelle J. Hooth and Suramya Waidyanatha
Toxicology and Applied Pharmacology (2020)
DOI: https://doi.org/10.1016/j.taap.2021.1153955 PMID: 33421504
Corrigendum to “Internal dose of vanadium in rats following repeated exposure to vanadyl sulfate and sodium orthovanadate via drinking water” Toxicology and Applied Pharmacology 412 (2021) Authors: James M. Harrington, Laura G. Haines, Keith E. Levine, Chamindu Liyanapatirana, Amal S. Essader, Reshan A. Fernando, Veronica G. Robinson, Georgia K. Roberts, Matthew D. Stout, Michelle J. Hooth and Suramya Waidyanatha PMID: 33905758
DOI: https://doi.org/10.22427/NTP-DATA-002-02993-0008-0000-3
Toxicology and Applied Pharmacology (2020)
DOI: https://doi.org/10.1016/j.taap.2021.1153955 PMID: 33421504
Corrigendum to “Internal dose of vanadium in rats following repeated exposure to vanadyl sulfate and sodium orthovanadate via drinking water” Toxicology and Applied Pharmacology 412 (2021) Authors: James M. Harrington, Laura G. Haines, Keith E. Levine, Chamindu Liyanapatirana, Amal S. Essader, Reshan A. Fernando, Veronica G. Robinson, Georgia K. Roberts, Matthew D. Stout, Michelle J. Hooth and Suramya Waidyanatha PMID: 33905758
DOI: https://doi.org/10.22427/NTP-DATA-002-02993-0008-0000-3
Systemic exposure and urinary excretion of vanadium following perinatal subchronic exposure to vanadyl sulfate and sodium metavanadate via drinking water
Suramya Waidyanatha, Frank X. Weber, James M. Harrington, Dawn M. Fallacara, Keith Levine, Veronica G. Robinson, Barney R. Sparrow, Matthew D. Stout, Reshan Fernando, Michelle J. Hooth, Guanhua Xie, Chamindu Liyanapatirana, Georgia K. Roberts
Toxciology Letters(2022) DOI: https://doi.org/10.1016/j.toxlet.2022.03.004
DOI: https://doi.org/10.22427/NTP-DATA-002-00048-0001-000-5
Toxciology Letters(2022) DOI: https://doi.org/10.1016/j.toxlet.2022.03.004
DOI: https://doi.org/10.22427/NTP-DATA-002-00048-0001-000-5
Study Data
Toxicity and Carcinogenicity Studies
2-week Evaluation of the Toxicity (C94043-01) of Sodium Metavanadate (13718-26-8) in Harlan Sprague-Dawley Rats Exposed via Dosed Water
Study Tables
- I01 - Animal Removal Summary (35 kB)
- I03 - Growth Curve (59 kB)
- I04 - Mean Body Weights and Survival (117 kB)
- I04G - Mean Body Weight Gain (54 kB)
- I05 - Clinical Observations Summary (110 kB)
- I06 - Mean Feed Consumption (155 kB)
- I07 - Mean Water Consumption (190 kB)
- I08 - Mean Test Compound Consumption (126 kB)
- PA06 - Organ Weights Summary (96 kB)
- PA46 - Gross Pathology Summary (401 kB)
- PA48 - Summary of Tissue Concentration (40 kB)
Individual Animal Data
- Individual Animal Body Weight Data (22 kB)
- Individual Animal Clinical Observations Data (36 kB)
- Individual Animal Consumption Data (56 kB)
- Individual Animal Gross Pathology Data (131 kB)
- Individual Animal Organ Weight Data (15 kB)
- Individual Animal Removal Reasons (12 kB)
- Individual Animal Tissue Concentration Data (7 kB)
2-week Evaluation of the Toxicity (C94043-02) of Sodium Metavanadate (13718-26-8) in B6C3F1/N Mice Exposed via Dosed Water
Study Tables
- I01 - Animal Removal Summary (35 kB)
- I03 - Growth Curve (57 kB)
- I04 - Mean Body Weights and Survival (116 kB)
- I04G - Mean Body Weight Gain (54 kB)
- I05 - Clinical Observations Summary (106 kB)
- I06 - Mean Feed Consumption (154 kB)
- I07 - Mean Water Consumption (190 kB)
- I08 - Mean Test Compound Consumption (126 kB)
- PA06 - Organ Weights Summary (96 kB)
- PA46 - Gross Pathology Summary (405 kB)
Individual Animal Data
4-Week Immunotoxicity Evaluation (I94043) of Sodium Metavanadate (13718-26-8) in Female B6C3F1/N Mice Exposed via Dosed Water
Supplemental Tables
- I01 - Animal Removal Summary (80 kB)
- I02 - Animal Removals (954 kB)
- I03 - Growth Curve (2 mB)
- I03C - Growth Curve (2 mB)
- I04 - Mean Body Weight Summary (314 kB)
- I04G - Mean Body Weight Gain (274 kB)
- I05 - Clinical Observations Summary (102 kB)
- I07 - Mean Water Consumption (303 kB)
- I08 - Mean Test Compound Consumption (243 kB)
- M03 - Peripheral Blood Leukocyte Cell Differential (64 kB)
- M04 - Hematology (61 kB)
- M06 - Spleen Immunophenotyping (85 kB)
- M07 - TDAR SRBC - Spleen AFC (46 kB)
- M08 - Serum IgM Antibody Titers to T-Dependent Antigen Sheep Erythrocytes (33 kB)
- M09 - Serum Antibody Concentrations for the T-Dependent Keyhole Lipet Hemocyanin (KLH) (37 kB)
- M11 - Spleen Cell Proliferative Response to Anti-CD3 Stimulation (34 kB)
- M12 - Cytotoxic T Cell Activity (40 kB)
- M15 - Natural Killer Cell Activity (39 kB)
- M19 - TDAR SRBC - ELISpot (35 kB)
- PA02 - Neoplastic Lesion Summary with Percent Incidence.pdf (140 kB)
- PA03 - Non-Neoplastic Lesion Summary with Percent Incidence (130 kB)
- PA05 - Incidence Rates of Neoplastic Lesions with Systemic Lesions Abridged (141 kB)
- PA06 - Organ Weights Summary (164 kB)
- PA10 - Statistical Analysis of Nonneoplastic Lesions (137 kB)
- PA14 - Individual Animal Pathology Data (855 kB)
- PA14 - Individual Animal Pathology Data (XML File) (110 kB)
- PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grade (130 kB)
- PA46 - Summary of Gross Pathology (170 kB)
3-Month (with Perinatal Exposure) Evaluation of the Toxicity (C94043) of Sodium Metavanadate (13718-26-8) in Harlan Sprague-Dawley Rats Exposed via Dosed Water
Study Tables
- I01 - Animal Removal Summary (79 kB)
- I02 - Animal Removals (2 mB)
- I03 - Growth Curve (1 mB)
- I03C - Growth Curve (1 mB)
- I04 - Mean Body Weight Summary (340 kB)
- I04G - Mean Body Weight Gain (291 kB)
- I05 - Clinical Observations Summary (287 kB)
- I05P - Pup Clinical Observations Summary (293 kB)
- I07 - Mean Water Consumption (350 kB)
- I08 - Mean Test Compound Consumption (273 kB)
- PA02R - Neoplastic Lesion Summary with Percent and Litter Incidence (397 kB)
- PA03R - Non-Neoplastic Lesion Summary with Percent and Litter Incidence (477 kB)
- PA05R - Incidence Rates of Neoplastic Lesions with Litter Incidence Systemic Lesions Abridged (398 kB)
- PA06 - Organ Weight Summary (142 kB)
- PA10R - Statistical Analysis of Nonneoplastic Lesions with Litter Incidence (433 kB)
- PA14 - Individual Animal Pathology Data (2 mB)
- PA18R - Non-Neoplastic Lesion Summary with Mean Severity Grade and Litter Incidence (477 kB)
- PA41 - Clinical Chemistry Summary (253 kB)
- PA43 - Hematology Summary (528 kB)
- PA44 - Urinalysis Data Summary (259 kB)
- PA46 - Summary of Gross Pathology (235 kB)
- PA48 - Summary of Tissue Concentration (48 kB)
- R01 - Multigeneration Cross Reference (2 mB)
- R02 - Reproductive Performance Summary (46 kB)
- R03 - Summary of Litter Data (105 kB)
- R06 - Andrology Summary (61 kB)
- R16 - Pubertal Markers Summary (72 kB)
- R19 - Pup Mean Body Weight Summary (272 kB)
- R19C - Pup Growth Curve (942 kB)
- R19G - Pup Mean Body Weight Gain (206 kB)
- Vaginal Cytology Markov Model (176 kB)
- Vaginal Cytology Plots (144 kB)
- Vaginal Cytology Summary (126 kB)
Individual Animal Data
- Individual Animal Andrology Data (10 kB)
- Individual Animal Body Weight Data (155 kB)
- Individual Animal Clinical Chemistry Data (16 kB)
- Individual Animal Clinical Observations Data (231 kB)
- Individual Animal Consumption Data (233 kB)
- Individual Animal Developmental Markers Data (37 kB)
- Individual Animal Gross Pathology Data (315 kB)
- Individual Animal Hematology Data (42 kB)
- Individual Animal Histopathology Data (107 kB)
- Individual Animal Litter Data (113 kB)
- Individual Animal Organ Weight Data (21 kB)
- Individual Animal Pup Body Weight Data (193 kB)
- Individual Animal Pup Clinical Observations Data (606 kB)
- Individual Animal Removal Reasons Data (23 kB)
- Individual Animal Reproductive Performance Data (8 kB)
- Individual Animal Tissue Concentration Data (7 kB)
- Individual Animal Urinalysis Data (13 kB)
- Individual Animal Whole Litter Weight Data (6 kB)
3-Month Evaluation of the Toxicity (C94043) of Sodium Metavanadate (13718-26-8) in B6C3F1 Mice Exposed via Dosed Water
Study Tables
- I01 - Animal Removal Summary (44 kB)
- I02 - Animal Removals (415 kB)
- I03 - Growth Curve (697 kB)
- I03C - Growth Curve (682 kB)
- I04 - Mean Body Weight Summary (220 kB)
- I04G - Mean Body Weight Gain (190 kB)
- I05 - Clinical Observations Summary (59 kB)
- I07 - Mean Water Consumption (248 kB)
- I08 - Mean Test Compound Consumption (196 kB)
- PA02 - Neoplastic Lesion Summary with Percent Incidence (390 kB)
- PA03 - Non-Neoplastic Lesion Summary with Percent Incidence (382 kB)
- PA05 - Incidence Rates of Neoplastic Lesions with Systemic Lesions Abridged (391 kB)
- PA06 - Organ Weights Summary (141 kB)
- PA08 - Statistical Analysis of Neoplastic Lesions (226 kB)
- PA10 - Statistical Analysis of Nonneoplastic Lesions (306 kB)
- PA14 - Individual Animal Pathology Data (2 mB)
- PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grade (382 kB)
- PA43 - Hematology Summary (293 kB)
- PA46 - Summary of Gross Pathology (227 kB)
- R06 - Andrology Summary (60 kB)
- Vaginal Cytology Markov Model (175 kB)
- Vaginal Cytology Plots (141 kB)
- Vaginal Cytology Summary (125 kB)
Individual Animal Data
- Individual Animal Andrology Data (9 kB)
- Individual Animal Body Weight Data (54 kB)
- Individual Animal Clinical Observations Data (55 kB)
- Individual Animal Consumption Data (95 kB)
- Individual Animal Gross Pathology Data (211 kB)
- Individual Animal Hematology Data (18 kB)
- Individual Animal Histopathology Data (84 kB)
- Individual Animal Organ Weight Data (15 kB)
- Individual Animal Removal Reasons Data (9 kB)