Perfluorooctane sulfonate (1763-23-1)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3031864
Publications
TOX-96
NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
A high-throughput toxicity screen of 42 per- and polyfluoroalkyl substances (PFAS) and functional assessment of migration and gene expression in human placental trophoblast cells
Bevin E. Blake, Brittany P. Rickard, and Suzanne E. Fenton
DOI: https://doi.org/10.22427/NTP-DATA-025-00001-0001-000-9
DOI: https://doi.org/10.22427/NTP-DATA-025-00001-0001-000-9
Toxicokinetics of Perfluorobutane Sulfonate (PFBS), Perfluorohexane-1-Sulphonic Acid (PFHxS), and Perfluorooctane Sulfonic Acid (PFOS) in Male and Female Hsd:Sprague Dawley SD Rats after Intravenous and Gavage Administration
Huang M.C., Dzierlenga A., Robinson V.G, Waidyanatha S, DeVito M.J, Eifrid M.A, Granville C.A., Gibbs S.T, Blystone C.R
DOI: https://doi.org/10.22427/NTP-DATA-002-00037-0001-000-3
DOI: https://doi.org/10.22427/NTP-DATA-002-00037-0001-000-3
Study Data
Toxicity and Carcinogenicity Studies
28-Day Evaluation of the Toxicity (C20617) of Perfluorooctane Sulfonate (PFOS) (1763-23-1) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E01 - Animal Removal Summary By Treatment Group (12 kB)
- E02 - Animals Removed from Experiment (66 kB)
- E03 - Growth Curves (363 kB)
- E04 - Mean Body Weights and Survival Table (16 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (215 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (227 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (141 kB)
- P11 - Statistical Analysis of Survival Data (27 kB)
- P14 - Individual Animal Pathology Data (279 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (217 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 kB)
- P40 - Survival Curves (399 kB)
- PA06 - Organ Weights Summary (118 kB)
- PA41 - Clinical Chemistry Summary (307 kB)
- PA43 - Hematology Summary (276 kB)
- PA45 - Liver Special Studies Summary (36 kB)
- PA48 - Summary of Tissue Concentration (73 kB)
- R06 - Andrology Summary (50 kB)
- R07 - Hormone Summary (68 kB)
- Results of Vaginal Cytology Study Using Transition Matrix Approach (44 kB)
- Summary of Estrous Stages and Cycle Data (54 kB)
- Vaginal Cytology Plot (17 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Non Neoplastic Pathology Data (43 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Individual Animal Andrology Data (7 kB)
- Individual Animal Clinical Chemistry Data (16 kB)
- Individual Animal Hematology Data (18 kB)
- Individual Animal Hormone Data (11 kB)
- Individual Animal Liver Special Studies Data (6 kB)
- Individual Animal Organ Weight Data (15 kB)
- Individual Animal Tissue Concentration Data (10 kB)
- Individual Vaginal Cytology Data (23 kB)
- Individual_Animal_PCR_Data (25 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (52 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Clinical Observations (4 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Perfluorooctane Sulfonate (1763-23-1) in Micronucleus Study G04004 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Perfluorooctane Sulfonate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A33826
Other NTP Studies
Toxicokinetic Evaluation (K10076) of Perfluorooctane Sulfonate (DTXSID3031864) in Rat
Data
- Annotated Group Parameters (71 kB)
- Annotated Individual Animal Data (47 kB)
- Summary Data (264 kB)