o-Chlorobenzalmalononitrile (2698-41-1)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9020297
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Bacterial Mutagenicity |
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Publications
TR-377
Toxicology and Carcinogenesis Studies of CS2 (94% o-Chlorobenzalmalononitrile, CASRN 2698-41-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
McGregor, D.B., Brown, A., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. II. 18 coded chemicals. Environ. Molec. Mutagen. Vol. 11 (1988) 91-118
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity (C55118) of o-Chlorobenzalmalononitrile (CS) (2698-41-1) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55118) of o-Chlorobenzalmalononitrile (CS) (2698-41-1) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of o-Chlorobenzalmalononitrile (CS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 704784
Summary Data
- G06 - Ames Summary Data (192 KB)
Genetic Toxicity Evaluation of o-Chlorobenzalmalononitrile (CS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 825580
Summary Data
- G06 - Ames Summary Data (141 KB)