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o-Chlorobenzalmalononitrile (2698-41-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9020297

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to o-Chlorobenzalmalononitrile (2698-41-1).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to o-Chlorobenzalmalononitrile (2698-41-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to o-Chlorobenzalmalononitrile (2698-41-1).
Bacterial Mutagenicity
View
  • Equivocal
View
  • Equivocal

Citation Information

NTP. o-Chlorobenzalmalononitrile (2698-41-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-377 Toxicology and Carcinogenesis Studies of CS2 (94% o-Chlorobenzalmalononitrile, CASRN 2698-41-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
McGregor, D.B., Brown, A., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. II. 18 coded chemicals. Environ. Molec. Mutagen. Vol. 11 (1988) 91-118

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C55118) of o-Chlorobenzalmalononitrile (CS) (2698-41-1) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55118) of o-Chlorobenzalmalononitrile (CS) (2698-41-1) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of o-Chlorobenzalmalononitrile (CS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 704784
Summary Data
Genetic Toxicity Evaluation of o-Chlorobenzalmalononitrile (CS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 825580
Summary Data

DTT Data Collections