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TR-377: o-Chlorobenzalmalononitrile (2698-41-1)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-377: o-Chlorobenzalmalononitrile (2698-41-1).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-377: o-Chlorobenzalmalononitrile (2698-41-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-377: o-Chlorobenzalmalononitrile (2698-41-1).
Bacterial Mutagenicity
View
  • Equivocal
View
  • Equivocal

Citation Information

NTP. TR-377: o-Chlorobenzalmalononitrile (2698-41-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-377 Toxicology and Carcinogenesis Studies of CS2 (94% o-Chlorobenzalmalononitrile, CASRN 2698-41-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C55118) of o-Chlorobenzalmalononitrile (CS) (2698-41-1) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55118) of o-Chlorobenzalmalononitrile (CS) (2698-41-1) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of o-Chlorobenzalmalononitrile (CS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 704784
Summary Data
Genetic Toxicity Evaluation of o-Chlorobenzalmalononitrile (CS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 825580
Summary Data