Perfluorodecanoic acid (335-76-2)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3031860
Publications
TOX-97
NTP Report on the Toxicity Studies of Perfluorinated Compounds: Carboxylates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
Immunotoxic and Hepatotoxic Effects of Perfluoro-n-decanoic Acid (PFDA) on Female Harlan Sprague–Dawley Rats and B6C3F1/N Mice when Administered by Oral Gavage for 28 Days
Rachel P. Frawley, Matthew Smith, Mark F. Cesta, Schantel Hayes-Bouknight, Chad Blystone, Grace E. Kissling, Shawn Harris & Dori Germolec.
Journal of Immunotoxicology (2018) DOI: https://doi.org/10.1080/1547691X.2018.1445145 PMID: 29514525
Journal of Immunotoxicology (2018) DOI: https://doi.org/10.1080/1547691X.2018.1445145 PMID: 29514525
A high-throughput toxicity screen of 42 per- and polyfluoroalkyl substances (PFAS) and functional assessment of migration and gene expression in human placental trophoblast cells
Bevin E. Blake, Brittany P. Rickard, and Suzanne E. Fenton
DOI: https://doi.org/10.22427/NTP-DATA-025-00001-0001-000-9
DOI: https://doi.org/10.22427/NTP-DATA-025-00001-0001-000-9
Toxicokinetics of Perfluorohexanoic acid (PFHxA), Perfluorooctanoic acid (PFOA), and Perfluorodecanoic Acid (PFDA) in Male and Female Hsd:Sprague Dawley SD Rats following Intravenous or Gavage Administration
Dzierlenga A.L, Robinson V.G, Waidyanatha S, DeVito M.J, Eifrid M.A, Gibbs S.T, Granville C.A, *Blystone C.R
DOI: https://doi.org/10.22427/NTP-DATA-002-00037-0002-000-4
DOI: https://doi.org/10.22427/NTP-DATA-002-00037-0002-000-4
Study Data
Toxicity and Carcinogenicity Studies
28-Day Evaluation of the Toxicity (C20615) of Perfluorodecanoic Acid (PFDA) (335-76-2) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E01 - Animal Removal Summary By Treatment Group (12 kB)
- E02 - Animals Removed from Experiment (67 kB)
- E03 - Growth Curves (371 kB)
- E04 - Mean Body Weights and Survival Table (16 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (225 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (35 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (238 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (154 kB)
- P11 - Statistical Analysis of Survival Data (27 kB)
- P14 - Individual Animal Pathology Data (282 kB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (224 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 kB)
- P40 - Survival Curves (417 kB)
- PA06 - Organ Weights Summary (118 kB)
- PA41 - Clinical Chemistry Summary (307 kB)
- PA43 - Hematology Summary (276 kB)
- PA45 - Liver Special Studies Summary (36 kB)
- PA48 - Summary of Tissue Concentration (73 kB)
- R06 - Andrology Summary (50 kB)
- R07 - Hormone Summary (68 kB)
- Results of Vaginal Cytology Study Using Transition Matrix Approach (42 kB)
- Summary of Estrous Stages and Cycle Data (59 kB)
- Vaginal Cytology Plot (17 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Non Neoplastic Pathology Data (46 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Female Individual Clinical Observations (2 kB)
- Individual Animal Andrology Data (7 kB)
- Individual Animal Clinical Chemistry Data (16 kB)
- Individual Animal Hematology Data (18 kB)
- Individual Animal Hormone Data (12 kB)
- Individual Animal Liver Special Studies Data (6 kB)
- Individual Animal Organ Weight Data (15 kB)
- Individual Animal Tissue Concentration Data (10 kB)
- Individual Vaginal Cytology Data (23 kB)
- Individual_Animal_PCR_Data (24 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (74 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Clinical Observations (4 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Perfluorodecanoic Acid (335-76-2) in Micronucleus Study G92006 in Harlan Sprague-Dawley Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Perfluorodecanoic Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A10025
Summary Data
- G06 - Ames Summary Data (81 KB)
Other NTP Studies
Toxicokinetic Evaluation (C20615) of Perfluorodecanoic Acid (335-76-2) in Harlan Sprague-Dawley Rats Exposed via Intravenous Injection and Gavage
Toxicokinetic Evaluation (K10214) of Perfluorodecanoic Acid (DTXSID3031860) in Rat
Data
- Annotated Group Parameters (19 kB)
- Annotated Individual Animal Data (122 kB)
- Original Data (41 kB)
- Summary Data (238 kB)