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1-Perfluorobutanesulfonic acid (375-73-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5030030

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to 1-Perfluorobutanesulfonic acid (375-73-5).
Micronucleus - Rats
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 1-Perfluorobutanesulfonic acid (375-73-5).
Bacterial Mutagenicity
View
  • Equivocal

Citation Information

NTP. 1-Perfluorobutanesulfonic acid (375-73-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TOX-96 NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
A high-throughput toxicity screen of 42 per- and polyfluoroalkyl substances (PFAS) and functional assessment of migration and gene expression in human placental trophoblast cells Bevin E. Blake, Brittany P. Rickard, and Suzanne E. Fenton
DOI: https://doi.org/10.22427/NTP-DATA-025-00001-0001-000-9
Toxicokinetics of Perfluorobutane Sulfonate (PFBS), Perfluorohexane-1-Sulphonic Acid (PFHxS), and Perfluorooctane Sulfonic Acid (PFOS) in Male and Female Hsd:Sprague Dawley SD Rats after Intravenous and Gavage Administration Huang M.C., Dzierlenga A., Robinson V.G, Waidyanatha S, DeVito M.J, Eifrid M.A, Granville C.A., Gibbs S.T, Blystone C.R
DOI: https://doi.org/10.22427/NTP-DATA-002-00037-0001-000-3
Unraveling Human Hepatocellular Responses to PFAS and Aqueous Film-Forming Foams (AFFFs) for Molecular Hazard Prioritization and In Vivo Translation Kevin A. Mauge-Lewis1,‡, Sreenivasa C. Ramaiahgari1,‡, Scott S. Auerbach1, Georgia K. Roberts1, Suramya Waidyanatha1, Suzanne E Fenton1, Dhiral P. Phadke2, Michele R. Balik-Meisner2, Arpit Tandon2, Deepak Mav2, Brian Howard2, Ruchir Shah2, Barney Sparrow3, Jenni Gorospe3, Stephen S. Ferguson1

‡These authors equally contributed to this study.
1Division of Translational Toxicology at the National Institute for Environmental Sciences, Research Triangle Park, North Carolina
2Sciome, Research Triangle Park, North Carolina
3Battelle, Columbus, Ohio

Environmental Science and Technology, (2025) DOI: https://doi.org/10.1021/acs.est.4c10595 PMID: 398893674 PMCID: PMC11823446

DOI: https://doi.org/10.22427/NTP-DATA-500-017-001-000-4

Study Data

Protocol

Toxicity and Carcinogenicity Studies

28-Day Evaluation of the Toxicity (C07040) of Perfluorobutane sulfonate (PFBS) (375-73-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Perfluorobutane Sulfonate (PFBS) (375-73-5) in Micronucleus Study G04006 in Harlan Sprague-Dawley Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Perfluorobutane Sulfonate (PFBS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A32037
Summary Data

DTT Data Collections