Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

1-Perfluorobutanesulfonic acid (375-73-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5030030

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to 1-Perfluorobutanesulfonic acid (375-73-5).
Micronucleus - Rats
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 1-Perfluorobutanesulfonic acid (375-73-5).
Bacterial Mutagenicity
View
  • Equivocal

Citation Information

NTP. 1-Perfluorobutanesulfonic acid (375-73-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TOX-96 NTP Report on the Toxicity Studies of Perfluorinated Compounds: Sulfonates Administered via Oral Gavage in Hsd: Sprague Dawley SD Rats
A high-throughput toxicity screen of 42 per- and polyfluoroalkyl substances (PFAS) and functional assessment of migration and gene expression in human placental trophoblast cells Bevin E. Blake, Brittany P. Rickard, and Suzanne E. Fenton
DOI: https://doi.org/10.22427/NTP-DATA-025-00001-0001-000-9
Toxicokinetics of Perfluorobutane Sulfonate (PFBS), Perfluorohexane-1-Sulphonic Acid (PFHxS), and Perfluorooctane Sulfonic Acid (PFOS) in Male and Female Hsd:Sprague Dawley SD Rats after Intravenous and Gavage Administration Huang M.C., Dzierlenga A., Robinson V.G, Waidyanatha S, DeVito M.J, Eifrid M.A, Granville C.A., Gibbs S.T, Blystone C.R
DOI: https://doi.org/10.22427/NTP-DATA-002-00037-0001-000-3

Study Data

Protocol

Toxicity and Carcinogenicity Studies

28-Day Evaluation of the Toxicity (C07040) of Perfluorobutane sulfonate (PFBS) (375-73-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Perfluorobutane Sulfonate (PFBS) (375-73-5) in Micronucleus Study G04006 in Harlan Sprague-Dawley Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Perfluorobutane Sulfonate (PFBS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A32037
Summary Data

DTT Data Collections