Reserpine (50-55-5)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7021237
Study Results
Chronic Bioassay Level of Evidence
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Mice | |
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Genetic Toxicology
Rodent Cytogenetics | |
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CA | SCE |
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Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity |
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SLRL |
Bacterial Mutagenicity |
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Publications
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Zimmering, S., Mason, J.M., and Valencia, R. Chemical mutagenesis testing in Drosophila. VII. Results of 22 coded compounds tested in larval feeding experiments. Environ. Molec. Mutagen. Vol. 14 (1989) 245-252
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of Reserpine (50-55-5) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Reserpine (50-55-5) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Reserpine (50-55-5) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Reserpine (50-55-5) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Reserpine (50-55-5) in Micronucleus Study 487993 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Reserpine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 450632
Summary Data
- G06 - Ames Summary Data (143 KB)