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N,N-Dimethylformamide (68-12-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6020515

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to N,N-Dimethylformamide (68-12-2).
Mammalian Cell Mutagenicity
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  • Negative
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  • Negative
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  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to N,N-Dimethylformamide (68-12-2).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to N,N-Dimethylformamide (68-12-2).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to N,N-Dimethylformamide (68-12-2).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. N,N-Dimethylformamide (68-12-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TOX-22 Toxicity Studies of N,N-Dimethylformamide (CASRN 68-12-2) Administered by Inhalation to F344/N Rats and B6C3F1Mice
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Myhr, B.C., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 103-194
Mitchell, A.D., Rudd, C.J., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for 63 coded chemicals tested at SRI International. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 37-102
McGregor, D.B., Brown, A., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. II. 18 coded chemicals. Environ. Molec. Mutagen. Vol. 11 (1988) 91-118

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C60913B) of Dimethylformamide (68-12-2) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
Pathology Tables
Individual Animal Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C60913B) of Dimethylformamide (68-12-2) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C60913B) of Dimethylformamide (68-12-2) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
Pathology Tables
Individual Animal Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C60913B) of Dimethylformamide (68-12-2) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C60913B) of Dimethylformamide (68-12-2) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C60913B) of Dimethylformamide (68-12-2) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Dimethylformamide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 814479
Summary Data

NTP Data Collections