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2-Chloronitrobenzene (88-73-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020280

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2-Chloronitrobenzene (88-73-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 2-Chloronitrobenzene (88-73-3).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2-Chloronitrobenzene (88-73-3).
Bacterial Mutagenicity
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  • Positive
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  • Positive
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  • Positive
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  • Positive
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  • Weakly Positive

Citation Information

NTP. 2-Chloronitrobenzene (88-73-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TOX-33 Toxicity Studies of 2-Chloronitrobenzene (CASRN 88-73-3) and 4-Chloronitrobenzene (CASRN 100-00-5) Administered by Inhalation to F344/N Rats and B6C3F1Mice
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Zimmering, S., Mason, J.M., Valencia, R., and Woodruff, R.C. Chemical mutagenesis testing in Drosophila. II. Results of 20 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 87-100
Zimmering, S., Mason, J.M., and Valencia, R. Chemical mutagenesis testing in Drosophila. VII. Results of 22 coded compounds tested in larval feeding experiments. Environ. Molec. Mutagen. Vol. 14 (1989) 245-252

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C62248) of 2-Chloronitrobenzene (88-73-3) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
Pathology Tables
Individual Animal Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C62248) of 2-Chloronitrobenzene (88-73-3) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C62248) of 2-Chloronitrobenzene (88-73-3) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C62248) of 2-Chloronitrobenzene (88-73-3) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 123419
Summary Data
Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 217675
Summary Data
Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 270911
Summary Data
Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 334206
Summary Data
Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 689524
Summary Data

Other NTP Studies

ADME/TK Evaluation (S0104) of 2-Chloronitrobenzene (88-73-3) in F344 Rats Exposed via Gavage Administration
Data Summary
ADME/TK Evaluation (S0191) of 2-Chloronitrobenzene (88-73-3) in F344 Rats Exposed via Topical Application
Data Summary
ADME/TK Evaluation (S0364) of 2-Chloronitrobenzene (88-73-3) in F344 Rats Exposed via Gavage Administration
Data Summary
ADME/TK Evaluation (S0365) of 2-Chloronitrobenzene (88-73-3) in Geriatric F344 Rats Exposed via Gavage Administration
Data Summary

DTT Data Collections