TR-606: Technical Report Pathology Tables and Curves

Pathology Tables, Survival and Growth Curves from NTP
Summary of Exposure Information, Short-Term, Long Term Studies

TR-606: alpha-Pinene

Summary of Exposure Information

Exposure Tables

• Alpha-Pinene Exposure Tables (574 KB)

Short-Term

3-Month Investigative Study Tables - Rats

• Estrous Cycle Plots (139 KB)
• I01 - Animal Removal Summary (81 KB)
• I02 - Animal Removals (442 KB)
• I03 - Growth Curve (581 KB)
• I03C - Growth Curve (546 KB)
• I04 - Mean Body Weight Summary (177 KB)
• I04G - Mean Body Weight Gain (164 KB)
• I05 - Clinical Observations Summary (108 KB)
• PA02 - Incidence Rates of Neoplasms by Anatomic Site (225 KB)
• PA03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (191 KB)
• PA05 - Incidence Rates of Neoplasms by Anatomic Site Systemic Lesions Abridged (225 KB)
• PA06 - Organ Weights Summary (80 KB)
• PA10- Statistical Analysis of Non-Neoplastic Lesions (214 KB)
• PA14 - Individual Animal Pathology Data (1 MB)
• PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (191 KB)
• PA46 - Summary of Gross Pathology (209 KB)
• PA48 - Summary of Internal Concentration (33 KB)
• R06 - Andrology Summary (97 KB)
• Vaginal Cytology CMTC Results (179 KB)
• Vaginal Cytology CMTC Results (11 KB)
• Vaginal Cytology Summary (9 KB)
• Vaginal Cytology Summary (121 KB)

3-Month Investigative Individual Animal Data - Rats

• Individual Animal Andrology Data (9 KB)
• Individual Animal Body Weight Data (52 KB)
• Individual Animal Clinical Observations Data (54 KB)
• Individual Animal Gross Pathology Data (28 KB)
• Individual Animal Internal Concentration (16 KB)
• Individual Animal Organ Weight Data (8 KB)
• Individual Animal Removal Reasons Data (9 KB)

3-Month Reproductive Study Tables - CD-1 Mice

• I01 - Animal Removal Summary (150 KB)
• I02 - Animal Removals (784 KB)
• I03 - Growth Curve (604 KB)
• I03C - Growth Curve (566 KB)
• I04 - Mean Body Weight Summary (180 KB)
• I04G - Mean Body Weight Gain (172 KB)
• I05 - Clinical Observations Summary (128 KB)
• PA02 - Incidence Rates of Neoplasms by Anatomic Site (109 KB)
• PA03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (109 KB)
• PA04 - Neoplasms by Individual Animal (1 MB)
• PA05 - Incidence Rates of Neoplasms by Anatomic Site Systemic Lesions Abridged (109 KB)
• PA06 - Organ Weights Summary (112 KB)
• PA07: Neoplasms By Individual Animal Systemic Lesions Abridged (1 MB)
• PA09 - Non-Neoplastic Lesions by Individual Animal (1 MB)
• PA10 - Statistical Analysis of Non-Neoplastic Lesions (115 KB)
• PA14 - Individual Animal Pathology Data (3 MB)
• PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (325 KB)
• PA46 - Summary of Gross Pathology (172 KB)
• R02 - Reproductive Performance Summary (109 KB)
• R09 - Uterine Content Summary (130 KB)

3-Month Reproductive Individual Animal Data - CD-1 Mice

• Individual Animal Body Weight Data (76 KB)
• Individual Animal Clinical Observations Data (82 KB)
• Individual Animal Gross Pathology Data (19 KB)
• Individual Animal Histopathology Data (14 KB)
• Individual Animal Organ Weight Data (10 KB)
• Individual Animal Removal Reasons Data (12 KB)
• Individual Animal Teratology Dam Data (8 KB)
• Individual Animal Teratology Fetal Weight Data (36 KB)
• Individual Animal Teratology Implant Findings Data (47 KB)

Long Term

3-Month Reproductive and Chronic Study Tables - Rats

• I01 - Animal Removal Summary (107 KB)
• I02 - Animal Removals (2 MB)
• I03 - Growth Curve (1 MB)
• I03C - Growth Curve (1 MB)
• I04 - Mean Body Weight Summary (451 KB)
• I04G - Mean Body Weight Gain (389 KB)
• I05 - Clinical Observations Summary (1 MB)
• PA02 - Incidence Rates of Neoplasms by Anatomic Site (777 KB)
• PA03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (1 MB)
• PA04 - Neoplasms by Individual Animal (14 MB)
• PA05 - Incidence Rates of Neoplasms by Anatomic Site Systemic Lesions Abridged (684 KB)
• PA06 - Organ Weights Summary (80 KB)
• PA07: Neoplasms By Individual Animal Systemic Lesions Abridged (13 MB)
• PA08 - Statistical Analysis of Primary Tumors (10 MB)
• PA09 - Non-Neoplastic Lesions by Individual Animal (22 MB)
• PA10 - Statistical Analysis of Non-Neoplastic Lesions (17 MB)
• PA11 - Statistical Analysis of Survival Data (122 KB)
• PA14 - Individual Animal Pathology Data (30 MB)
• PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (1 MB)
• PA40C - Survival Curves (461 KB)
• PA46 - Summary of Gross Pathology (1 MB)
• PA48 - Summary of Internal Concentration (34 KB)
• R01 - Multigeneration Cross Reference (392 KB)
• R02 - Reproductive Performance Summary (75 KB)
• R09 - Uterine Content Summary (101 KB)

3-Month Reproductive and Chronic Individual Animal Data Rats

• Individual Animal Body Weight Data (515 KB)
• Individual Animal Clinical Observations Data (390 KB)
• Individual Animal Gross Pathology Data (1 MB)
• Individual Animal Histopathology Data (908 KB)
• Individual Animal Internal Concentration (19 KB)
• Individual Animal Organ Weight Data (10 KB)
• Individual Animal Removal Reasons Data (29 KB)
• Individual Animal Reproductive Performance Data (9 KB)
• Individual Animal Teratology Dam Data (9 KB)
• Individual Animal Teratology Fetal Weight Data (37 KB)
• Individual Animal Teratology Implant Findings Data (48 KB)

3-Month and Chronic Study Tables - B6C3F1/N Mice

• I01 - Animal Removal Summary (94 KB)
• I02 - Animal Removals (1 MB)
• I03 - Growth Curve (1 MB)
• I03C - Growth Curve (930 KB)
• I04 - Mean Body Weight Summary (598 KB)
• I04G - Mean Body Weight Gain (267 KB)
• I05 - Clinical Observations Summary (806 KB)
• PA02 - Incidence Rates of Neoplasms by Anatomic Site (838 KB)
• PA03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (1 MB)
• PA04 - Neoplasms by Individual Animal (14 MB)
• PA05 - Incidence Rates of Neoplasms by Anatomic Site Systemic Lesions Abridged (709 KB)
• PA06 - Organ Weights Summary (112 KB)
• PA07 - Neoplasms By Individual Animal Systemic Lesions Abridged (13 MB)
• PA08 - Statistical Analysis of Primary Tumors (7 MB)
• PA09 - Non-Neoplastic Lesions by Individual Animal (18 MB)
• PA10 - Statistical Analysis of Non-Neoplastic Lesions (12 MB)
• PA11 - Statistical Analysis of Survival Data (197 KB)
• PA14 - Individual Animal Pathology Data (24 MB)
• PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (1 MB)
• PA40C - Survival Curve (421 KB)
• PA46 - Summary of Gross Pathology (1 MB)
• PA48 - Summary of Internal Concentration (33 KB)

3-Month and Chronic Individual Animal Data - B6C3F1/N Mice

• Individual Animal Body Weight Data (421 KB)
• Individual Animal Clinical Observations Data (316 KB)
• Individual Animal Gross Pathology Data (906 KB)
• Individual Animal Histopathology Data (747 KB)
• Individual Animal Internal Concentration (22 KB)
• Individual Animal Organ Weight Data (6 KB)
• Individual Animal Removal Reasons Data (22 KB)