TOX-99: Gum guggul extract (GUMGUGGULEXT)
Publications
TOX-99
Toxicity Studies of Gum Guggul Extract (CASRN GUMGUGGULEXT) Administered by Gavage to Harlan Sprague Dawley Rats and B6C3F1 Mice
Study Data
Toxicity and Carcinogenicity Studies
28-Day Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (369 kB)
- E04 - Mean Body Weights and Survival Table (12 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (21 kB)
- P04 - Neoplasms by Individual Animal (146 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (22 kB)
- P08 - Statistical Analysis of Primary Tumors (7 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (138 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (59 kB)
- P14 - Individual Animal Pathology Data (163 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (21 kB)
- P40 - Survival Curves (395 kB)
- PA06 - Organ Weights Summary (153 kB)
- PA41 - Clinical Chemistry Summary (508 kB)
- PA43 - Hematology Summary (582 kB)
- PA49 - Cytochrome Activity Summary (78 kB)
- R07 - Hormone Summary (102 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Non Neoplastic Pathology Data (12 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Individual Animal Clinical Chemistry Data (24 kB)
- Individual Animal Cytochrome Activity Data (14 kB)
- Individual Animal Hematology Data (32 kB)
- Individual Animal Hormone Data (14 kB)
- Individual Animal Organ Weight Data (20 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (10 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
28-Day Evaluation of the Prechronic Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT ) in B6C3F1 Mice Exposed Via Gavage
Study Tables
- E03 - Growth Curves (406 kB)
- E04 - Mean Body Weights and Survival Table (13 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 kB)
- P04 - Neoplasms by Individual Animal (138 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (23 kB)
- P08 - Statistical Analysis of Primary Tumors (8 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (74 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (24 kB)
- P14 - Individual Animal Pathology Data (155 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (20 kB)
- P40 - Survival Curves (390 kB)
- PA06 - Organ Weights Summary (152 kB)
- PA41 - Clinical Chemistry Summary (174 kB)
- PA49 - Cytochrome Activity Summary (78 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (18 kB)
- Female Individual Animal Neoplastic Pathology Data (2 kB)
- Female Individual Animal Non Neoplastic Pathology Data (2 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Individual Animal Clinical Chemistry Data (17 kB)
- Individual Animal Cytochrome Activity Data (9 kB)
- Individual Animal Organ Weight Data (15 kB)
- Male Individual Animal Body Weight Data (18 kB)
- Male Individual Animal Non Neoplastic Pathology Data (3 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
3-Month Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in Harlan Sprague-Dawley Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (455 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34 kB)
- P04 - Neoplasms by Individual Animal (231 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (237 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (191 kB)
- P14 - Individual Animal Pathology Data (265 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35 kB)
- P40 - Survival Curves (435 kB)
- PA06 - Organ Weights Summary (153 kB)
- PA41 - Clinical Chemistry Summary (508 kB)
- PA43 - Hematology Summary (582 kB)
- PA49 - Cytochrome Activity Summary (78 kB)
- R06 - Andrology Summary (51 kB)
- R07 - Hormone Summary (102 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (35 kB)
- Female Individual Animal Neoplastic Pathology Data (2 kB)
- Female Individual Animal Non Neoplastic Pathology Data (27 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (19 kB)
- Female Individual Clinical Observations (2 kB)
- Individual Animal Andrology Data (8 kB)
- Individual Animal Clinical Chemistry Data (24 kB)
- Individual Animal Hematology Data (32 kB)
- Individual Animal Hormone Data (14 kB)
- Individual Animal Organ Weight Data (20 kB)
- Male Individual Animal Body Weight Data (35 kB)
- Male Individual Animal Non Neoplastic Pathology Data (27 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (19 kB)
- Male Individual Clinical Observations (2 kB)
3-Month Evaluation of the Toxicity (C20605) of Gum Guggul Extract (GUMGUGGULEXT) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (419 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- E05 - Clinical Observations Summary (14 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (28 kB)
- P04 - Neoplasms by Individual Animal (193 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (125 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (48 kB)
- P14 - Individual Animal Pathology Data (364 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (29 kB)
- P40 - Survival Curves (433 kB)
- PA06 - Organ Weights Summary (152 kB)
- PA41 - Clinical Chemistry Summary (174 kB)
- PA49 - Cytochrome Activity Summary (78 kB)
- R06 - Andrology Summary (51 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (50 kB)
- Female Individual Animal Neoplastic Pathology Data (2 kB)
- Female Individual Animal Non Neoplastic Pathology Data (8 kB)
- Female Individual Animal Survival Data (16 kB)
- Female Individual Animal Terminal Body Weight Data (27 kB)
- Individual Animal Andrology Data (8 kB)
- Individual Animal Clinical Chemistry Data (17 kB)
- Individual Animal Organ Weight Data (15 kB)
- Male Individual Animal Body Weight Data (50 kB)
- Male Individual Animal Non Neoplastic Pathology Data (5 kB)
- Male Individual Animal Survival Data (16 kB)
- Male Individual Animal Terminal Body Weight Data (27 kB)
- Male Individual Clinical Observations (2 kB)