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TR-337: Nitrofurazone (59-87-0)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Equivocal Evidence, Male, Rats
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  • Clear Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • No Evidence, Male, Mice
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  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-337: Nitrofurazone (59-87-0).
Micronucleus - Mice
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  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-337: Nitrofurazone (59-87-0).
Mammalian Cell Mutagenicity
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  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-337: Nitrofurazone (59-87-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-337: Nitrofurazone (59-87-0).
Bacterial Mutagenicity
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  • Positive

Citation Information


NTP. TR-337: Nitrofurazone (59-87-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-337 Toxicology and Carcinogenesis Studies of Nitrofurazone (CASRN 59-87-0) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Nitrofurazone (59-87-0) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Nitrofurazone (59-87-0) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Nitrofurazone (59-87-0) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Nitrofurazone (59-87-0) in Female B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Nitrofurazone (59-87-0) in Micronucleus Study A59017 in B6C3F1 Mice
Genetic Toxicity Evaluation of Nitrofurazone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 364720
Summary Data