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Nitrofurazone (59-87-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5020944

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Equivocal Evidence, Male, Rats
View
  • Clear Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
View
  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Nitrofurazone (59-87-0).
Micronucleus - Mice
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  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Nitrofurazone (59-87-0).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Nitrofurazone (59-87-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Nitrofurazone (59-87-0).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Nitrofurazone (59-87-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-337 Toxicology and Carcinogenesis Studies of Nitrofurazone (CASRN 59-87-0) in F344/N Rats and B6C3F1 Mice (Feed Studies)
IMM90011 NTP Summary Reports on Immunotoxicology Vol. 1, No. 1-15: Immunotoxicity of Nitrofurazone in Female B6C3F1 Mice
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Teratologic Evaluation of Nitrofurazone Administered to New Zealand White Rabbits on Gestational Days 6-19
Teratologic Evaluation of Nitrofurazone Administered to CD-1 Mice on Gestational Days 6 through 15
Myhr B.C., McGregor, D., Bowers, L., Riach, C., Brown, A., Edwards, I., McBride, D., Martin, R., and Caspary, W.J. L5178Y mouse lymphoma cell mutation assay results with 41 compounds. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 138-167
Anderson, B.E., Zeiger, E., Shelby, M.D., Resnick, M.A., Gulati, D.K., Ivett, J.L., and Loveday, K.S. Chromosome aberration and sister chromatid exchange test results with 42 chemicals. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 55-137

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Nitrofurazone (59-87-0) in Male F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nitrofurazone (59-87-0) in Female F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nitrofurazone (59-87-0) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Nitrofurazone (59-87-0) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Nitrofurazone (59-87-0) in Micronucleus Study A59017 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Nitrofurazone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 364720
Summary Data

Other NTP Studies

2-Week Immunotoxicity Evaluation (IMM90011) of Nitrofurazone (59-87-0) in Female B6C3F1 Mice Exposed via Gavage
B6CF1 Mice Individual and Summary Data
Prenatal Developmental Toxicity Study (TER85092) of Nitrofurazone (59-87-0) in Swiss CD-1 Mice Exposed via Dosed Feed
Individual and Summary Data
Prenatal Developmental Toxicity Study (TER87093) of Nitrofurazone (59-87-0) in New Zealand White Rabbits Exposed via Gavage
Individual and Summary Data
Screen for Developmental Toxicity in Zebrafish- Study 1
Results

NTP Data Collections