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TR-341: Nitrofurantoin (67-20-9)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-341: Nitrofurantoin (67-20-9).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-341: Nitrofurantoin (67-20-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-341: Nitrofurantoin (67-20-9).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-341: Nitrofurantoin (67-20-9).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive

Citation Information

NTP. TR-341: Nitrofurantoin (67-20-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-341 Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C55196) of Nitrofurantoin (67-20-9) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55196) of Nitrofurantoin (67-20-9) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 131452
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 133668
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 451594
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 626123
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 674104
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 962072
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 981362
Summary Data