U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

TR-341: Nitrofurantoin (67-20-9)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-341: Nitrofurantoin (67-20-9).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-341: Nitrofurantoin (67-20-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-341: Nitrofurantoin (67-20-9).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-341: Nitrofurantoin (67-20-9).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive
View
  • Positive

Citation Information


NTP. TR-341: Nitrofurantoin (67-20-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-341 Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 131452
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 133668
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 451594
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 626123
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 674104
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 962072
Summary Data
Genetic Toxicity Evaluation of Nitrofurantoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 981362
Summary Data