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TR-448: Isobutyl nitrite (542-56-3)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Some Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-448: Isobutyl nitrite (542-56-3).
Micronucleus - Mice
View
  • Male: Positive
    Female: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-448: Isobutyl nitrite (542-56-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-448: Isobutyl nitrite (542-56-3).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-448: Isobutyl nitrite (542-56-3).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive
View
  • Positive

Citation Information


NTP. TR-448: Isobutyl nitrite (542-56-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-448 Toxicology and Carcinogenesis Studies of Isobutyl Nitrite (CASRN 542-56-3) in F344 Rats and B6C3F1 Mice (Inhalation Studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C61052B) of Isobutyl Nitrite (542-56-3) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C61052B) of Isobutyl Nitrite (542-56-3) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C61052B) of Isobutyl Nitrite (542-56-3) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C61052B) of Isobutyl Nitrite (542-56-3) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Isobutyl Nitrite (542-56-3) in Micronucleus Study A87798 in B6C3F1 Mice
Genetic Toxicity Evaluation of Isobutyl Nitrite in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 234350
Summary Data
Genetic Toxicity Evaluation of Isobutyl Nitrite in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 507924
Summary Data
Genetic Toxicity Evaluation of Isobutyl Nitrite in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 983397
Summary Data