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TR-465: Phenolphthalein (77-09-8)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Male, Rats
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to TR-465: Phenolphthalein (77-09-8).
Rodent Cytogenetics
CA
  • View
    • Negative (Nonstandard Protocol)
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-465: Phenolphthalein (77-09-8).
Micronucleus - Mice
View
  • Male: Positive
    Female: Positive
View
  • Male: Positive
    Female: Positive
View
  • Male: Positive
    Female: Positive
View
  • Male: Positive
    Female: Positive
View
  • Male: Positive
    Female: Positive
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-465: Phenolphthalein (77-09-8).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-465: Phenolphthalein (77-09-8).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Equivocal

Citation Information

NTP. TR-465: Phenolphthalein (77-09-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-465 Toxicology and Carcinogenesis Studies of Phenolphthalein (CASRN 77-09-8) in F344 Rats and B6C3F1 Mice (Feed Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C55798) of Phenolphthalein (77-09-8) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C55798) of Phenolphthalein (77-09-8) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55798B) of Phenolphthalein (77-09-8) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C55798B) of Phenolphthalein (77-09-8) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Phenolphthalein (77-09-8) in Micronucleus Study A13109 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Phenolphthalein (77-09-8) in Micronucleus Study A20259 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Phenolphthalein (77-09-8) in Micronucleus Study A34828 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Phenolphthalein (77-09-8) in Micronucleus Study A93351 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Phenolphthalein (77-09-8) in Micronucleus Study A93723 in P16(INK4A)/(+/-) (C57BL/6) Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Phenolphthalein (77-09-8) in Micronucleus Study A93901 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Phenolphthalein in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 041772
Summary Data
Genetic Toxicity Evaluation of Phenolphthalein in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 768193
Summary Data
Genetic Toxicity Evaluation of Phenolphthalein in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A71314
Summary Data
Genetic Toxicity Evaluation of Phenolphthalein in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A99430
Summary Data