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TR-565: Milk thistle extract (84604-20-6)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-565: Milk thistle extract (84604-20-6).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-565: Milk thistle extract (84604-20-6).
Bacterial Mutagenicity
View
  • Positive
View
  • Negative
View
  • Negative
View
  • Negative
View
  • Positive
View
  • Positive

Citation Information


NTP. TR-565: Milk thistle extract (84604-20-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-565 Toxicology and Carcinogenesis Studies of Milk Thistle Extract (CASRN 84604-20-6) in F344/N Rats and B6C3F1 Mice (Feed studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C20008) of Milk Thistle Extract (84604-20-6) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C20008) of Milk Thistle Extract (84604-20-6) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C20008) of Milk Thistle Extract (84604-20-6) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Milk Thistle Extract (84604-20-6) in Micronucleus Study A73501 in B6C3F1 Mice
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A21904
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41673
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A42260
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44499
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A78884
Summary Data
Genetic Toxicity Evaluation of Milk Thistle Extract in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G99059
Summary Data