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Diallyl phthalate (131-17-9)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
View
  • Equivocal Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal, Male, Mice
View
  • Equivocal, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Diallyl phthalate (131-17-9).
Rodent Cytogenetics
CA SCE
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Diallyl phthalate (131-17-9).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Diallyl phthalate (131-17-9).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Diallyl phthalate (131-17-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Diallyl phthalate (131-17-9).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Diallyl phthalate (131-17-9).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. Diallyl phthalate (131-17-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-242 Carcinogenesis Bioassay of Diallyl Phthalate (CASRN 131-17-9) in B6C3F1 Mice (Gavage Study)
TR-284 Toxicology and Carcinogenesis Studies of Diallylphthalate (CASRN 131-17-9) in F344/N Rats (Gavage Studies)
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
Myhr, B. and Caspary, W. Chemical mutagenesis at the TK locus in L5178Y mouse lymphoma cells. I. Results for 31 coded compounds in the National Toxicology Program. Environ. Molec. Mutagen. Vol. 18 (1991) 51-83
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Diallyl Phthalate (131-17-9) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Diallyl Phthalate (131-17-9) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Diallyl Phthalate (131-17-9) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Diallyl Phthalate (131-17-9) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Diallyl Phthalate (131-17-9) in Micronucleus Study 730162 in B6C3F1 Mice
Genetic Toxicity Evaluation of Diallyl Phthalate (131-17-9) in Micronucleus Study A49968 in B6C3F1 Mice
Genetic Toxicity Evaluation of Diallyl Phthalate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 079950
Summary Data
Genetic Toxicity Evaluation of Diallyl Phthalate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 258261
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0228) of Diallyl phthalate (131-17-9) in F344 Rats and B6C3F1 Mice Exposed via Gavage Administration or Intravenous Injection