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Cytembena (21739-91-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5020368

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Positive, Male, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Negative, Male, Mice
View
  • Negative, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Cytembena (21739-91-3).
Rodent Cytogenetics
CA SCE
  • View
    • Negative (Nonstandard Protocol)
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Cytembena (21739-91-3).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Cytembena (21739-91-3).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Cytembena (21739-91-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Cytembena (21739-91-3).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Cytembena (21739-91-3).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Cytembena (21739-91-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-207 Carcinogenesis Bioassay of Cytembena (CASRN 21739-91-3)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
Ivett, J.L., Brown, B.M., Rodgers, C., Anderson, B.E., Resnick, M.A., Zeiger, E. Chromosomal aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro IV: Results for 15 chemicals Environ. Molec. Mutagen. Vol. 14 (1989) 165-187

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Cytembena (21739-91-3) in Male F344 Rats Exposed via Intraperitoneal Injection
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Cytembena (21739-91-3) in Female F344 Rats Exposed via Intraperitoneal Injection
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Cytembena (21739-91-3) in Male B6C3F1 Mice Exposed via Intraperitoneal Injection
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Cytembena (21739-91-3) in Female B6C3F1 Mice Exposed via Intraperitoneal Injection
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Cytembena (21739-91-3) in Micronucleus Study 983684 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cytembena in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 379904
Summary Data

NTP Data Collections