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2,6-Dichloro-p-phenylenediamine (609-20-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7020427

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to 2,6-Dichloro-p-phenylenediamine (609-20-1).
Rodent Cytogenetics
CA SCE
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2,6-Dichloro-p-phenylenediamine (609-20-1).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 2,6-Dichloro-p-phenylenediamine (609-20-1).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2,6-Dichloro-p-phenylenediamine (609-20-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 2,6-Dichloro-p-phenylenediamine (609-20-1).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2,6-Dichloro-p-phenylenediamine (609-20-1).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive

Citation Information

NTP. 2,6-Dichloro-p-phenylenediamine (609-20-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-219 Carcinogenesis Bioassay of 2,6-Dichloro-p-Phenylenediamine (CASRN 609-20-1) in F344 Rats and B6C3F1 Mice (Feed Study)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Male F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Female F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2,6-Dichloro-p-phenylenediamine (609-20-1) in Micronucleus Study 538041 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2,6-Dichloro-p-phenylenediamine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 010183
Summary Data
Genetic Toxicity Evaluation of 2,6-Dichloro-p-phenylenediamine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 949384
Summary Data

DTT Data Collections