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Ethyl methanesulfonate (62-50-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6025309

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Ethyl methanesulfonate (62-50-0).
Rodent Cytogenetics
CA
  • View
    • Positive (Nonstandard Protocol)
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Ethyl methanesulfonate (62-50-0).
Micronucleus - Mice
View
  • Male: Positive
View
  • Male: Positive
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Ethyl methanesulfonate (62-50-0).
Micronucleus - Rats
View
  • Male: Positive
View
  • Male: Positive
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Ethyl methanesulfonate (62-50-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology In Vivo Alkaline Comet Assay Rats study conclusions related to Ethyl methanesulfonate (62-50-0).
In Vivo Alkaline Comet Assay - Rats
View
  • Male: Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Ethyl methanesulfonate (62-50-0).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Ethyl methanesulfonate (62-50-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
Witt KL, Livanos E, Kissling GE, Torous DK, Caspary W, Tice RR, Recio L. Comparison of flow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals. Mutat Res. 2008 Jan 8;649(1-2):101-13. Epub 2007 Aug 11.

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Ethyl Methanesulfonate (62-50-0) in DNA Damage Study G20304B in Crl:CD (SD) Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ethyl Methanesulfonate (62-50-0) in Micronucleus Study A45799 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ethyl Methanesulfonate (62-50-0) in Micronucleus Study A84681 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ethyl Methanesulfonate (62-50-0) in Micronucleus Study F45799 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ethyl Methanesulfonate (62-50-0) in Micronucleus Study F84681 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ethyl Methanesulfonate (62-50-0) in Micronucleus Study G20304 in Wistar Han Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Ethyl Methanesulfonate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 764747
Summary Data

DTT Data Collections