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Dichlorvos (62-73-7)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Negative, Female, Rats
View
  • Equivocal Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Negative, Male, Mice
View
  • Negative, Female, Mice
View
  • Clear Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Dichlorvos (62-73-7).
Rodent Cytogenetics
CA SCE
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Dichlorvos (62-73-7).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Dichlorvos (62-73-7).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Dichlorvos (62-73-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dichlorvos (62-73-7).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. Dichlorvos (62-73-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-010 Bioassay of Dichlorvos for Possible Carcinogenicity (CASRN 62-73-7)
TR-342 Toxicology and Carcinogenesis Studies of Dichlorvos (CASRN 62-73-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Myhr B.C., McGregor, D., Bowers, L., Riach, C., Brown, A., Edwards, I., McBride, D., Martin, R., and Caspary, W.J. L5178Y mouse lymphoma cell mutation assay results with 41 compounds. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 138-167
Anderson, B.E., Zeiger, E., Shelby, M.D., Resnick, M.A., Gulati, D.K., Ivett, J.L., and Loveday, K.S. Chromosome aberration and sister chromatid exchange test results with 42 chemicals. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 55-137

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Dichlorvos (62-73-7) in Male Osborne-Mendel Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Dichlorvos (62-73-7) in Female Osborne-Mendel Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Dichlorvos (62-73-7) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Dichlorvos (62-73-7) in Female B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C00113B) of Dichlorvos (62-73-7) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C00113B) of Dichlorvos (62-73-7) in B6C3F1 Mice Exposed via Gavage