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2-Chloromethylpyridine hydrochloride (6959-47-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1020308

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Negative, Male, Mice
View
  • Negative, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to 2-Chloromethylpyridine hydrochloride (6959-47-3).
Rodent Cytogenetics
CA SCE
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2-Chloromethylpyridine hydrochloride (6959-47-3).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 2-Chloromethylpyridine hydrochloride (6959-47-3).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2-Chloromethylpyridine hydrochloride (6959-47-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 2-Chloromethylpyridine hydrochloride (6959-47-3).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2-Chloromethylpyridine hydrochloride (6959-47-3).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. 2-Chloromethylpyridine hydrochloride (6959-47-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-178 Bioassay of 2-(Chloromethyl)pyridine Hydrochloride for Possible Carcinogenicity (CASRN 6959-47-3)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila. VIII. Reexamination of equivocal results. Environ. Molec. Mutagen. Vol. 19 (1992) 227-234

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 2-Chloromethylpyridine Hydrochloride (6959-47-3) in Male F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2-Chloromethylpyridine Hydrochloride (6959-47-3) in Female F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2-Chloromethylpyridine Hydrochloride (6959-47-3) in Male B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2-Chloromethylpyridine Hydrochloride (6959-47-3) in Female B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2-Chloromethylpyridine Hydrochloride (6959-47-3) in Micronucleus Study A65556 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2-Chloromethylpyridine Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 374887
Summary Data

DTT Data Collections